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HIV/AIDS Clinical Trials

A listing of HIV/AIDS medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (12) clinical trials

Virological Suppression in HIV Positive Patients Involved in a Novel Standardized Adherence Protocol

This study will look at virologically suppression of patients with HIV who receive pharmacist or case management care.

Phase

Effect of Evolocumab on Coronary Endothelial Function

To evaluate the effect of the PCSK9 inhibitor evolocumab on coronary and systemic endothelial function, systemic biomarkers of endothelial function and of inflammation, and echocardiographic measures of left ventricular diastolic and systolic properties in subjects who are HIV+. Potential participants will be asked to undergo a screening MRI exam. Those ...

Phase

An Efficacy and Safety Study of shRNA-modified CD34+ Cells in HIV-infected Patients.

CD34+ cells will be isolated from mobilized PBMC of HIV patients. The cells will be lentivirally transduced with multiplexed shRNAs in the same vector that target CCR5 and HIV genome. Such modified cells will be infused back to the patients who have received bulsufan preconditioning before infusion. The patients will ...

Phase

Safety and Immunogenicity Study of DNA.HTI and MVA.HTI in HIV-1-positive Patients(AELIX-002)

AELIX Therapeutics in collaboration with IrsiCaixa has developed a novel immunogen, termed HTI which was designed as an immunogen for T cells to be used as a a therapeutic HIV vaccine that could help HIV infected individuals to control viral replication in the absence of antiretroviral treatment. HTI is a ...

Phase

A Couple-based HIV Prevention Intervention to Promote HIV Protection Among Latino Male Couples

Latino men who have sex with men (MSM) continue to be disproportionately affected by HIV. Experiences of stigma, discrimination, marginalization, sexual objectification, negative cultural perceptions of homosexuality, and cultural values such as 'familismo' and 'machismo' elevate their vulnerability to HIV infection. Many Latino MSM use substances as a way to ...

Phase N/A

The Prevention Options for Women Evaluation Research (POWER) Cohort

PrEP will be delivered to young women according to emerging national guidelines in family planning clinics (Kisumu, Kenya), youth friendly clinics (Johannesburg, South Africa), and mobile youth friendly clinics (Cape Town, South Africa). The investigators will evaluate PrEP delivery and follow cohorts of young women at each clinic location to ...

Phase N/A

Behavioral Economics Incentives to Support HIV Treatment Adherence in Sub-Saharan Africa

It is imperative to find ways to boost ART adherence in sub-Saharan Africa where adherence rates have been found to decline over time, and where treatment options such as second-line regimens are limited. A promising tool is the use of incentives based on insights from behavioral economics (BE) for healthy ...

Phase N/A

Application of IV 99mTc-tilmanocept for Imaging of Macrophage-specific Inflammation

People living with HIV (PLWH) have an increased risk of cardiovascular disease (CVD) compared to individuals without HIV. Increased systemic immune activation and arterial inflammation are thought to contribute to this increased risk by affecting the highly inflammatory process of atherosclerotic plaque formation and progression. This study will evaluate whether ...

Phase N/A

A Pragmatic Trial of An Adaptive eHealth HIV Prevention Program for Diverse Adolescent MSM

Adolescent (ages 13-18) men who have sex with men (AMSM) experience a dramatic health disparity as they represent 2% of young people but account for almost 80% of HIV diagnoses in youth. Despite this disproportionate burden, current evidence-based HIV prevention programs focus primarily on adults and heterosexual youth. Because issues ...

Phase N/A

Study of Safety Tolerability and Immunogenicity of Gardasil 9 in Immunocompromised Patients

This is a single-center, open-label study on safety, tolerability and immunogenicity of Gardasil9 in 18 to 45 year-old HIV patients, in 18 to 55 year-old solid-organ transplant (SOT) patients. This study will enrol 140 HIV patients with CD4+ (cluster of differentiation 4) count of >200cells/mm and 170 SOT patients, all ...

Phase