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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (15) clinical trials

Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth

The primary goals of this proposal are to investigate the etiological mechanisms associated with antidepressant-related dysfunctional emotional arousal and to characterize baseline neurobiological risk factors that predict the development of dysfunctional emotional arousal in treatment seeking youth with a family history of BD. Antidepressants have moderate benefit for treating mood ...

Phase N/A

Dopamine D2 and D3 Receptor Occupancy and Clinical Response in Older Patients With Schizophrenia

Positron Emission Tomography (PET) studies have demonstrated that a therapeutic window of dopamine D2/3 receptor occupancy (60-80%) is associated with clinical response in younger patients with schizophrenia. This observation has been used to predict the therapeutic dose range and contributed to current recommended antipsychotic doses. To date, there is no ...

Phase N/A

Jump Step - A Participatory Approach to Physical Activity & Mental Wellness

Mental disorders, including anxiety and depression, contribute more than either cardiovascular disease or cancer to the burden of disease worldwide. Individuals with chronic diseases and major depression use more health resources, have higher degrees of functional disability, and experience higher productivity losses, compared to their counterparts without major depression. Within ...

Phase N/A

Light-Therapy in the Treatment of the Acute Phase of the Bipolar Type II Depression

Bipolar type II depression is a very frequent condition for which we still have a significant lack of acute treatments. There is now consistent evidence that light-therapy treatment produced a significant decrease of depressive symptoms for seasonal and non-seasonal unipolar depression. But there are no long-term studies of light therapy ...

Phase N/A

Double Blind Randomized Controlled H1 Coil In Subjects With Bipolar Depression

The purpose of the study is to explore the efficacy and safety of H1-Coil deep brain rTMS in subjects with bipolar depression , currently treated with mood stabilizer and previously unsuccessfully treated with antidepressant medications

Phase N/A

Myths About Bipolar Affective Disorder: The Role of Structured Group Psychoeducation Therapy

Methods: Effect psychoeducation: Study population - 30 patients diagnosed with BAD treated in the outpatient clinic, in a state of remission will be evaluated with the Hamilton Rating Scale for Depression, Young Mania Rating Scale, and will then participate in 7 weekly sessions of brief structured psycho education therapy Control ...

Phase N/A

Improving Outcome in Schizophrenia Through Identification of Genetic Risk Factors

The goals of this study are to replicate previous findings of genetic predictors of response to clozapine and other antipsychotic drugs.

Phase N/A

A Randomized Controlled Trial on the Effect of Exercise on Physical Cognitive and Affective Function in Dementia Subjects

Studies have shown conflicting results of the effect of exercise on dementia patients. The aim of this study is to examine the role of physical activity on the risk of cognitive impairment and dementia in older persons. To promote the benefits of aerobic exercise on dementia patients and encourage exercise ...

Phase N/A

Evaluation of Efficacy and Safety of Long-acting Risperidone Microspheres in Patients With Schizophrenia or Other Psychotic Disorders When Switching From Typical Antipsychotic (Oral/Depot) or Atypical Oral Other Than Risperidone

The purpose of this study is to evaluate the efficacy, tolerability and safety of patients on long-acting Risperidone microshpheres injection. The major advantage of long-acting injection over oral medication is facilitation of compliance in medication taking. Non-compliance is very common among schizophrenic and is a frequent cause of relapse.

Phase N/A

A Shared Decision Making Training for Inpatients With Schizophrenia

Patients suffering from schizophrenia who attend the communication skills program engage more deeply in therapeutic reasoning and treatment decisions. This results in stronger preferences to participate, greater perceived involvement and better long term adherence compared to patients who do not attend the training.

Phase N/A