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Affective Disorders Clinical Trials

A listing of Affective Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (16) clinical trials

A clinical trial seeking patients for a research study of Haloperidol, Paliperidone Palmitate Injection (PP1M), Perphenazine, Oral Risperidone, Quetiapine, Paliperidone Palmitate Injection (PP3M), Aripiprazole, Oral Paliperidone ER, Olanzapine

A Prospective, matched-control, Randomized (assignment of study drug by chance), open-label, flexible-dose, study in participants with recent-onset schizophrenia or schizophreniform disorder to compare disease progression and disease modification following treatment with PP long-acting injection (once-monthly followed by 3-month injections) or OAP (Any of the following 7 OAPs are permitted: aripiprazole, ...


Evaluation of the Genetics of Bipolar Disorder

Bipolar affective disorder is a severe, heritable condition affecting about one percent of the population. The mode of inheritance is poorly understood and probably involves multiple loci of small to moderate effect. In this project, we use genetic mapping and sequencing methods to identify genetic markers and variations that contribute ...

Phase N/A

A clinical trial seeking patients for a research study for the treatment of Magnetic Resonance Imaging, Genoty[e, Cognitioin Disorder, Psychosis

This protocol is meant to provide a matrix for multiple, simultaneous brain imaging investigations using magnetic resonance imaging (MRI) at 3.0 Tesla (3T). We intend to study regional brain structure, physiology, and biochemistry in living human subjects, both healthy and ill. Based on multiple clinical, neuropathological, and functional neuroimaging studies, ...

Phase N/A

A clinical trial to evaluate treatments using Placebo Oral Tablet, N-Acetylcysteine, Gabapentin for patients

Bipolar disorder (BD) is the Axis I psychiatric condition most strongly associated with substance use disorder (SUD); diagnostic co-occurrence is particularly high between BD and alcohol use disorder (AUD). Individuals with co-occurring SUD and BD (SUD+BD) have substantially worse clinical outcomes than those with either BD or SUD alone. Nonetheless, ...


A clinical trial sponsored by Janssen Research & Development, LLC for a research study for the treatment of Bipolar Disorder

The primary purpose of this study is to compare, over 24 months, the time spent with clinically significant mood symptoms (ie, mania, depression), as measured by the Longitudinal Interval Follow-Up Evaluation (LIFE) and the Psychiatric Status Rating Scale (PSR), in offspring of bipolar parents with and without at least mild ...

Phase N/A

A Phase 3 clinical study for patients using ALKS 3831, Olanzapine

In the US adolescent subjects starting at age 16 will be enrolled. In the EU, subjects age 18 and older will be enrolled.


A clinical research study of BI 409306, Placebo for the treatment of Psychosis

To investigate the efficacy, safety and tolerability of BI 409306 once daily compared to placebo given for 52 weeks to subjects with attenuated psychosis syndrome.


A clinical trial seeking patients for a research study of Minocycline

The investigators are doing this research study to find out if minocycline alone, N-acetyl cysteine (NAC) alone, or the combination of minocycline and NAC can help people with bipolar depression when added to lithium. The investigators also want to find out if minocycline, NAC, and the combination of minocycline and ...


A clinical trial seeking patients for a research study for the treatment of Endogenous depression, Bipolar Disorder, Depression

This trial will compare the trajectories of improvement for three different patterns of twice-daily rTMS in major depression: two daily sessions of dorsomedial prefrontal rTMS delivered at 0 min vs. 30 min vs. 60 min intervals.

Phase N/A

A clinical trial sponsored by National Institute of Mental Health (NIMH) for a research study for the treatment of Endogenous depression, Post-Traumatic Stress Disorder, Schizophrenia, Bipolar Disorder, Major depression

Objective: The mission of Human Brain Collection Core (HBCC) is to gain insight into the causes and mechanisms of mental disorders. Study Population: To be able to conduct this research, we obtain brain and other tissues from deceased individuals with and without psychiatric disorders. Study Design: This protocol provides the ...

Phase N/A