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Gastroenteritis Clinical Trials

A listing of Gastroenteritis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (21) clinical trials

Benralizumab for Eosinophilic Gastritis

Primary Objective: To assess the efficacy of repeat subcutaneous (SC) doses of benralizumab, compared with placebo, to reduce eosinophilic inflammation in the gastrointestinal tract of patients with EG Secondary Objectives: To assess changes in endoscopic score/histological features/blood and biopsy eosinophil counts/clinical symptoms/esophageal, gastric, and duodenal tissue transcriptome changes/ before and ...

Phase

Optimising Rotavirus Vaccine in Aboriginal Children

Australian Indigenous children, particularly those living in remote communities, suffer a disproportionately high burden of rotavirus gastroenteritis disease. Despite the introduction of rotavirus vaccine into the Northern Territory (NT) Immunisation Schedule in 2006, the rate of hospitalization for rotavirus in NT Aboriginal children < 5 years continues to be high, ...

Phase

Optimizing the Management of Acute Diarrhoeal Disease

Many children admitted to hospital in Botswana without bloody diarrhoea are presumed to have viral gastroenteritis and so not treated with antibiotics - but they may indeed have a treatable cause for their illness. The investigators will conduct a randomized trial to see if rapid testing using novel methods to ...

Phase

Optimal Human Dose for GII.2 Norovirus (Snow Mountain) Challenge Studies

This is a phase I, randomized, double blind, as well as partially blinded (for Cohort 4), placebo-controlled safety, illness, and infection study of a new experimental human challenge stock of the Norovirus genogroup II, genotype 2 (GII.2) isolate designated Snow Mountain virus (SMV), administered to healthy adults 18-49 years of ...

Phase

Oral Nitazoxanide in Acute Gastroenteritis in Australian Indigenous Children

This is a multi-centre (RDH and ASH), phase IV, double-blind, randomised, placebo-controlled trial of oral NTZ for the treatment of acute gastroenteritis requiring admission to hospital. Four hundred children aged between three months and less than five years of age will be enrolled. Study participation would be from the point ...

Phase

Lactose-free Milk in Infants With Acute Diarrhea in a Developing Country

Acute gastroenteritis is a major cause of pediatric morbidity and mortality accounting for 15 % of all childhood death worldwide, and is a major public health burden, especially in developing countries. A recent Cochrane review of 33 randomized or quasi-randomized trials reported a modest reduction in the duration of diarrhea ...

Phase N/A

Phase 1 Study of dmLT ID Vaccination in Healthy Adults

This is a randomized, double-blinded, single site outpatient Phase 1 study in healthy adults to determine the safety and immunogenicity of an ETEC candidate vaccine, attenuated recombinant dmLT from ETEC, administered by the ID route. The sample size has been determined based on the historic sample, not on power calculations. ...

Phase

CEGIR 7809: Effect of Elemental Diet on Adult Patients With Eosinophilic Gastroenteritis

This prospective interventional study will investigate the effect of a six week elemental diet in adult patients with Eosinophilic Gastroenteritis

Phase N/A

Efficacy and Safety of a Pentavalent Rotavirus Vaccine (BRV-PV) Against Severe Rotavirus Gastroenteritis in Niger

The study is a double-blinded, randomized, placebo-controlled, trial with two groups of infants receiving vaccine or placebo to assess the efficacy and safety of BRV-PV. Three doses of BRV-PV containing ≥ Log10 5.6 FFU/Dose of each serotype G1, G2, G3, G4 and G9 will be administered at 4 week intervals ...

Phase

Safety Reactogenicity and Immunogenicity of Heat-stable Rotavirus Vaccine (HSRV) in Adults and Infants

Rotaviruses are the leading cause of severe, dehydrating diarrhea and related deaths in children aged less than 5 years worldwide and are reported to infect nearly every child by the age of 5 years. About 90% of all rotavirus-associated fatalities occur in low income countries in Africa and Asia and ...

Phase