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Hemodialysis Clinical Trials

A listing of Hemodialysis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (144) clinical trials

Effect of Reducing Phosphorus Absorption on Cardiac Biomarkers in Hemodialysis Patients

Cardiovascular disease is one of the leading causes of morbidity and mortality in patient with chronic kidney disease(CKD), accounting for more than 50% of all deaths.When myocardial cells get injured, cardiac biomarkers will be released into the circulation. Elevated cardiac biomarkers have been observed in patients with various degrees of ...

Phase N/A

RCT of Paclitaxel DEB Compared to Standard PTA in Dialysis Fistula

Prospective multicenter randomized (1:1) Investigator Sponsored Trial, in which 150 consecutive patients candidates for percutaneous intervention of haemodialysis access will be randomly assigned to one of two study arms: Treatment Arm: paclitaxel drug-eluting balloon (DEB) dilatation using the APERTO-balloon Control Arm: standard percutaneous transluminal angioplasty (PTA). The aim is to ...

Phase N/A

Environmental Exposure to Lead and Its Health Effects on Patients With Maintenance Hemodialysis

One thousand patients with LHD who have no history of exposure to lead will be observed for 18 months. Blood lead level(BLL), biochemical data, hemoglobin, albumin, Cr, high sensitivity C-reactive protein (HsCRP), and blood cell counts are assessed at baseline. The morbidity and mortality are recorded in detail. Then, one ...

Phase N/A

Complement Activation During Hemodialysis in Atypical Hemolytic Uraemic Syndrome as Underlying Kidney Disease

Atypical hemolytic uraemic syndrome is caused by defects in the regulating factors in the alternative pathway of the complement system. Triggering can cause an uncontrolled complement activation with endothelial damage and thrombotic micro-angiopathy, especially in the kidneys. This can result in endstage renal failure. Complement activation during hemodialysis has been ...

Phase N/A

Drug Eluting Balloon for Prevention of Hemodialysis Access Restenosis

In Canada, there are over 20,000 patients with chronic end-stage renal disease (ESRD)on long-term hemodialysis and the number is increasing rapidly.The creation of hemodialysis access (HA) (also called "lifeline" for dialysis patients) has become the most common type of vascular surgery. These HA are frequently complicated by dysfunction after their ...

Phase N/A

Effect of Malnutrition on the Prognosis in Hemodialysis Patients

Malnutrition is known to affect their prognosis in hemodialysis patients. Furthermore, recent studies indicate that malnutrition is associated with inflammation and atherosclerosis in these patients. In this study we examine the effect of malnutrition and/or inflammation on atherosclerosis and 5-year survival rate in 600 hemodialysis patients.

Phase N/A

Removal of Protein Bound Uremic Toxins by Modified Plasma Separation and Adsorption Combined With Hemodialysis

Measurements of uremic protein bound substances before and after mFPSA and a preceding routine hemodialysis session.

Phase N/A

Influence of Nutritional and Inflammational Status on Survival of Hemodialysis Patients

prospective longitudinal measurements of nutritional status parameters (body composition by BIA, anthropometry and biochemical indexes), inflammatory response (CRP, inflammatory cytokines (IL-1, IL-6, IL-10),IGF-1, leptin and NOx blood levels) and morbidity and mortality data collection over 2 year period in patients receiving chronic hemodialysis.

Phase N/A

Serum NGAL Levels in Hemodialysis (HD) Patients; Relation to Iron Status HD and Intravenous (IV) Iron Administration

Serum and urine levels of the siderophore binding protein neutrophil gelatinase associated lipocalin (NGAL) are increased in a number of renal diseases, but has not been evaluated yet in dialysis patients. Since NGAL is suggested to be related to inflammatory processes and iron homeostasis, which are a major problem in ...

Phase N/A

A Novel Catheter Lock Solution for Treatment of Tunneled Hemodialysis Catheter-Associated Bacteremia

The primary objective is to investigate the ability of systemic intravenous antibiotic plus antibiotic/anti-biofilm (i.e. N-acetylcysteine) lock catheter technique in eradicating uncomplicated catheter associated bacteremia and salvaging the infected vascular catheter. Secondary objectives include duration to clearance of bacteremia, future recurrence of bacteremia, need for catheter removal and death.

Phase