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Liver Transplantation Clinical Trials

A listing of Liver Transplantation medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (38) clinical trials

A Study To Confirm Efficacy and Safety of Terlipressin in HRS Type 1

This is a Phase 3, randomized, double-blind, placebo-controlled, multicenter pivotal trial of terlipressin in subjects with HRS type 1. HRS is a rare syndrome of marked renal dysfunction in patients with cirrhosis, decompensated liver disease, and portal hypertension. HRS type 1 is characterized by a rapid progressive renal impairment and ...

Phase

WP01 - Normothermic Liver Preservation

A multicenter randomized controlled trial to compare the efficacy of ex-vivo normothermic machine profusion with static cold storage in human liver transplantation.

Phase

Australian and New Zealand Massive Transfusion Registry

Severe and unstopped blood loss can occur for a number of different reasons including after a serious injury, delivery of a baby and following other medical and surgical emergencies. The investigators understanding of how to best treat people with serious bleeding is still incomplete, with many questions remaining. These include ...

Phase N/A

Seladelpar (MBX-8025) in Subjects With Primary Biliary Cholangitis (PBC)

Primary: To evaluate the safety and efficacy of MBX-8025 2 mg, 5 mg, and 10 mg over 8 weeks of treatment Secondary: To evaluate the safety and efficacy of MBX-8025 2 mg, 5 mg, and 10 mg over 12 and 26 weeks of treatment To evaluate the safety and efficacy ...

Phase

Non-Invasive Rapid Assessment of Patients With Liver Transplants Using Magnetic Resonance Imaging With LiverMultiScan

Long-term survival after solid organ transplantation has increased during the last decade due to improvements in surgical technique, peri-operative care, and more efficient immunosuppression (IS) (1). However, transplant recipients still exhibit higher morbidity and mortality than the general population. One of the main causes are co-morbidities which are negatively influenced ...

Phase N/A

CNI-free "Bottom"-up Immunosuppression in Patients Undergoing Liver Transplantation

The risk of developing chronic renal failure after liver transplantation (LT) in the pre-MELD era was approximately 20% after 5 years, associated with the use of CNI and a 4-fold increased mortality risk. Besides pre-transplant factors associated with end-stage hepatic disease that influence renal function (hepatorenal syndrome [HRS]), there are ...

Phase

Efficacy of Everolimus in Combination With Tacrolimus in Liver Transplant Recipients

This trial will evaluate the efficacy of Everolimus in combination tacrolimus versus a standard immunosuppressive regimen concerning kidney function in liver transplant recipients.

Phase

The Mycophenolate Pregnancy Registry

The Mycophenolate Pregnancy Registry is designed as a prospective, observational registry collecting data regarding mycophenolate exposure during pregnancy, and pregnancy outcomes, fetal and infant outcomes after exposure. Early and later term pregnancy outcomes will be solicited at selected gestational time points. Structural and functional birth defects identified in the perinatal ...

Phase N/A