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Hepatitis C; Chronic Clinical Trials

A listing of Hepatitis C; Chronic medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (61) clinical trials

People with Hepatitis C Virus are asked to participate in a research study being conducted by Montefiore Medical Center.

Phase N/A

The body’s immune system usually becomes active when the body is fighting off an infection or disease. If an immune system is active for a long period of time, it may lead to problems such as heart, liver, and kidney disease. Many people who inject drugs are also infected with ...

Phase N/A

Hepatitis C is an infectious disease affecting primarily the liver, caused by the hepatitis C virus (HCV). HCV is spread primarily by blood-to-blood contact associated with intravenous drug use, poorly sterilized medical equipment and transfusions. An estimated 150-200 million people worldwide are infected with hepatitis C. The infection is often ...

Phase N/A

To explore the antiviral efficacy of combination therapy with sofosbuvir/ledipasvir fixed-dose combination ribavirin for 12 or 24 weeks in patients with advanced liver disease. Study designed with A cohort and B cohort.

Phase N/A

The purpose of this study is to evaluate the safety and effectiveness of an FDA-approved study drug as a sleep aid as compared to placebo (an inactive substance) in the treatment of insomnia associated with interferon-induced insomnia in patients with chronic hepatitis C (CHC). In addition, another purpose of this ...

Phase N/A

"Real Life" Evaluation of Efficacy and Safety of DAAs for the Treatment of HCV in Egypt

Clinical trials are performed under optimal conditions where patients are highly selected with no co-morbidity, clinical supervision is provided by the best specialists in the field, and strict protocols are used to enhance patients' compliance. Thus, results may not be generalizable to real-world clinical practice. Observational studies are now gaining ...

Phase N/A

'Fibrosis in the Lost Hepatitis C Population - Track Trace and Treat'

Objective To coordinate active tracing of chronic hepatitis C patients lost to follow-up to inform them about there disease severity and treatment options. Study design: This is a prospective cohort study, which will start as a pilot study in the Radboudumc Population: lost to follow-up chronic hepatitis C patients in ...

Phase N/A

Re-treatment of HCV Following DAA Failure

-Introduction Oral drugs, termed collectively as 'Direct-acting anti-viral agents' (DAAs), are the standard-of-care for HCV treatment. In India, four DAAs, namely sofosbuvir (SOF), daclatasvir (DCV), ledipasvir (LDV) and velpatasvir (VEL), are marketed. Initially, people were treated using SOF in combination with ribavirin with or without pegylated-interferon (Peg-IFN). Thereafter, HCV treatment ...

Phase N/A

Management of Patients With Hepatitis C in a Public Health Care Setting: The Punjab Model

An algorithm was developed using SOF-based regimens to treat all patients (RKD). Genotyping is not recommended for patients without cirrhosis of liver and they are being treated with SOF+DCV for 12-weeks, while genotyping is recommended for patients with cirrhosis of liver (Figure 1). Patients with liver cirrhosis and genotype 3 ...

Phase N/A

DAA Therapy in Pediatric Patients With Chronic Hepatitis C

Consecutive chronic hepatitis C (HCV) infected children [age: 12 to <18 years; both treatment-nave (TN) and treatment-experienced, (TE)] are being enrolled. Genotyping is not recommended for non-cirrhotic or TN patients and were treated with SOF+DCV for 12-weeks, while genotyping is recommended for patients with cirrhosis and TE patients. Patients with ...

Phase N/A