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Hepatitis C; Chronic Clinical Trials

A listing of Hepatitis C; Chronic medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (61) clinical trials

Postmarketing Surveillance of the Safety and Effectiveness of Daclatasvir and Asunaprevir for the Treatment of Chronic HCV Genotype 1B Infection in the Routine Clinical Practice in Korea

The primary objective of this study is to describe the safety of the combination of Daklinza (daclatasvir) and Sunvepra (asunaprevir) when used for the treatment of chronic hepatitis C (CHC) genotype 1b patients in real-life conditions when used according to its registered indications.

Phase N/A

Surveillance for Antiviral Resistant Variants in Chronic Hepatitis C Patients

To analyse for resistance-associated HCV variants in DAA-nave HCV patients using population and ultra-deep pyrosequencing (UDPS). Resistance associated variants will be analysed by qualitative and quantitative methods both pre-treatment and on-treatment. To determine whether in the absence of drug pressure there is variation in the prevalence of naturally occurring resistance ...

Phase N/A

Impact of DAA Uptake in Controlling HCV Epidemic and Modeling Interventions for HCV Elimination Among HIV-infected Persons in San Diego

A study that aims to quantify the state of DAA uptake and its impact on the HCV epidemic among PLWH in San Diego, and to characterize negative predictors of DAA treatment uptake among PLWH in San Diego. Retrospective and prospective data from UCSD Owen Clinic will be utilized to calculate ...

Phase N/A

Mild Hypothermia and Acute Kidney Injury in Liver Transplantation

This study is a single-blinded, randomized controlled trial of mild hypothermia during liver transplantation to provide protection from AKI. Participants will be randomized to normothermia (36.5-37.5 C) versus mild hypothermia (34-35 C) during a portion of the liver transplant operation. The protocol is based on preliminary data from rodent models ...

Phase N/A

Transmission of Chronic Hepatitis C in Pregnancy

The treatment of chronic hepatitis C virus infection has dramatically advanced in recent years, with the availability of multiple interferon-free treatment regimens that result in cure in over 95% of treatment nave individuals with 8 -12 weeks of therapy. Despite these advances, however, the natural history and treatment of HCV ...

Phase N/A

Epidemiology of Chronic Hepatitis C and Disease Modelling

Hepatitis C (HCV) is a major health problem amongst people who inject drugs (PWID) and have limited contact with health care services. Halfway houses (HH) serve to reintegrate former drug users into society. Strategies to eliminate HCV must focus on screening for HCV amongst HH The aim is to determine ...

Phase N/A

Evaluation of HCV Viremia Testing Approaches Among PWID in Georgia

A major step in identifying HCV infected individuals in Georgia has already been implemented by providing rapid anti-HCV testing for people who inject drugs (PWID) at HRS. However, access to HCV confirmatory viremia testing remains limited as PWID must be referred to treatment centers for testing. Two novel approaches to ...

Phase N/A

Study of Daclatasvir-based Therapy in Chinese Participants With Chronic Hepatitis C (CHC)

Study is a non-interventional, prospective, multicenter post marketing surveillance study to determine the safety of daclatasvir based therapy

Phase N/A

People With CHC Who Achieved a Sustained Virological Response Following Therapy With Direct Acting Antiviral Agents

We intend to observe up to 350 patients with chronic HCV infection who have successfully eradiated HCV following therapy with direct acting antiviral agents and describe the clinical, virological, laboratory, histological and immunological outcomes following eradication of HCV. Subjects will be recruited from two sources: 1) subjects who have already ...

Phase N/A

Response Guided Treatment With Direct Acting Anti-Viral Medications for Chronic HCV Infection

Treatment of HCV infection is directed at achieving sustained virological response (SVR), defined as the continued absence of detectable HCV RNA for 12 or more weeks after completion of therapy Given the limited resources available for the costly DAA treatment, implementation of a response-guided treatment (RGT) model to individualize length ...

Phase N/A