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Fungal Infections Clinical Trials

A listing of Fungal Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (10) clinical trials

CD101 Compared to Caspofungin Followed by Oral Step Down in Subjects With Candidemia and/or Invasive Candidiasis

The purpose of this study is to determine if intravenous CD101 is safe and effective in the treatment of candidemia and/or invasive candidiasis when compared to caspofungin (followed by oral fluconazole).

Phase

A Study of the Safety and Efficacy of Posaconazole Versus Voriconazole for the Treatment of Invasive Aspergillosis (MK-5592-069)

The purpose of this study is to evaluate the safety and efficacy of posaconazole versus voriconazole in the treatment of adults and adolescents with invasive aspergillosis (IA).

Phase

Ph II of Non-myeloablative Allogeneic Transplantation Using TLI & ATG In Patients w/ Cutaneous T Cell Lymphoma

Non-myeloablative approach for allogeneic transplant is a reasonable option, especially given that the median age at diagnosis is 55-60 years and frequently present compromised skin in these patients, which increases the risk of infection. Therefore, we propose a clinical study with allogeneic HSCT using a unique non-myeloablative preparative regimen, TLI/ATG, ...

Phase

Prophylaxis With Caspofungin in High-Risk Liver Transplantation

This is a non-comparative, open, multisite prospective estimation study to evaluate the efficacy and safety of caspofungin in the prophylactic treatment of adults who have received an orthotopic liver transplant and are at high risk of developing an invasive fungal infection. It is expected that the proportion of high-risk liver ...

Phase

Early Diagnosis of Aspergillosis in Patients at High Risk of Fungal Infection Caused by Treatment for Hematologic Cancer or Other Disease

OBJECTIVES: Primary - Determine the test characteristics of galactomannan (GM) ELISA using serum and bronchoalveolar lavage fluid (BALF) collected from patients at high risk of invasive fungal infection. - Determine the test characteristics of aspergillus PCR using blood and BALF samples collected from these patients. - Evaluate the role of ...

Phase N/A

Pharmacokinetics and Safety of Intravenous Posaconazole (MK-5592) in Chinese Participants at High Risk for Invasive Fungal Infections (MK-5592-120)

The purpose of this study is to evaluate the pharmacokinetics and safety of posaconazole intravenous solution in Chinese participants at high risk for invasive fungal infections. Neutropenic participants undergoing chemotherapy for acute myelogenous leukemia or myelodysplastic syndromes will be enrolled in the study.

Phase

Optimized Diagnostics for Improved Therapy Stratification in Invasive Fungal Infections

Samples from immunosuppressed patients with febrile neutropenia will be taken: at the start of neutropenic fever after 24 hours after 48 hours before the start of antimycotic therapy, if pertinent at the end of antimycotic therapy, if pertinent The results ot analyses by a panfungal PCR screening assay developed at ...

Phase N/A

Pharmacokinetics of Posaconazole (Noxafil ) as Prophylaxis for Invasive Fungal Infections

In 2014, the new intravenous and solid oral formulation of posaconazole were marketed. This offers new treatment possibilities, specifically in patients previously unable to attain adequate exposure to posaconazole solution. To the opinion of the researchers, only limited data are available on the pharmacokinetics (PK) of the new formulations of ...

Phase

Combination Treatment of 5% Natamycin and 1% Voriconazole in Fungal Keratitis

PROTOCOL FOR SUBMISSION AND APPROVAL OF RESEARCH PROJECT TITLE Combination treatment of 5% Natamycin and 1% Voriconazole in fungal keratitis: a Prospective Randomized double masked clinical trial STUDY LOCATION LV Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, Andhra Pradesh, India INVESTIGATORS Dr Merle Fernandes Consultant, Cornea and Anterior Segment Service ...

Phase

Effect of Different Colistin Doses on Clinical Outcome of Pediatric Cancer Patients With Gram Negative Infections

The aim of this study is to: Evaluate the clinical outcome of two different dosing regimen of IV colistin in the treatment of children with multidrug resistant gram-negative infections or sepsis. To estimate the frequency of colistin associated adverse effects. To correlate the serum colistin concentration and MIC to microbiological ...

Phase