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Hereditary Angioedema Clinical Trials

A listing of Hereditary Angioedema medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (15) clinical trials

The purpose of this clinical research study to test how well and how safe an investigational medication works in children and adolescent with HAE. Winthrop University Hospital Clinical Trials Center is conducting this clinical research study for children and adolescents, ages 2- 15 years old who have been diagnosed with ...

Phase N/A

Winthrop University Hospital Clinical Trials Center is Seeking participants that are at least 16 years of age and have been diagnosed with Acute Hereditary Angioedema. Hereditary Angioedema (HAE) is a very rare and potentially life-threatening genetic condition that occurs in about 1 in 10,000 to 1 in 50,000 people. HAE ...

Phase

Winthrop University Hospital Clinical Trials Center is seeking volunteers with inadequately controlled Hereditary Angioedema (HAE) for a clinical research study to test a medication already approved by the Food and Drug Administration (FDA) to investigate the safety and effectiveness of a higher dosage not approved by the FDA. Patient Inclusion ...

Phase N/A

Biomarker for Hereditary Angioedema Disease Type 1

Hereditary angioedema is a rare inherited disorder characterized by recurrent episodes of the accumulation of fluids outside of the blood vessels, blocking the normal flow of blood or lymphatic fluid and causing rapid swelling of tissues in the hands, feet, limbs, face, intestinal tract, or airway. Usually, this swelling is ...

Phase N/A

Study to Assess the Tolerability and Safety of Ecallantide in Children and Adolescents With Hereditary Angioedema

This pilot study is an open-label, non-randomized, single-arm study to evaluate the tolerability and safety of a single SC administration of ecallantide in up to approximately 10 pediatric subjects with HAE during an initial acute attack. The study is planned to enroll subjects 2 through 15 years of age who ...

Phase

Efficacy and Safety of BCX7353 to Prevent Angioedema Attacks in Subjects With Hereditary Angioedema

This 2-part study will evaluate the safety and efficacy of an oral treatment, BCX7353, in preventing angioedema attacks in subjects with hereditary angioedema (HAE). In Part 1 of the study, eligible subjects will be randomized to receive oral BCX7353 or placebo for 4 weeks. Assuming successful completion of Part 1, ...

Phase

Study of BCX7353 as a Treatment for Attacks of Hereditary Angioedema

This 3-part study will evaluate the efficacy and safety of an oral kallikrein inhibitor, BCX7353, in the treatment angioedema attacks in subjects with Type I or II hereditary angioedema (HAE). In each study part, subjects will treat 3 attacks with BCX7353 (2 attacks) or placebo (1 attack), in a randomly ...

Phase

Firazyr Patient Registry (Icatibant Outcome Survey - IOS)

The Firazyr and Cinryze patient registry is a multicenter, prospective, observational study for patients treated with Firazyr and/or Cinryze in countries where it is currently approved. The entry of participants in the Firazyr and Cinryze Registry is at the discretion of the physician and the participant and is not a ...

Phase N/A

A Long Term Safety Study of BCX7353 in Hereditary Angioedema

This is an open-label study to evaluate the long term safety and effectiveness of oral treatment with BCX7353 in preventing acute angioedema attacks in patients with Type I and Type II HAE.

Phase