Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters
 

Heart Defect Clinical Trials

A listing of Heart Defect medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (51) clinical trials

An Integrative-"Omics" Study of Cardiomyopathy Patients for Diagnosis and Prognosis in China

Identification of novel biomarkers is needed to improve the diagnosis and prognosis of cardiomyopathy. Also,the marked variation of genes which is still unclear, may influence clinical outcomes is determined in part by genetic heterogeneity of the systemic response to pathological process. Specific aim: Proteomics, microRNA-seq and metabolomics will be to ...

Phase N/A

Non Syndromic Congenital Heart Defect and Array-CGH in Prenatal Diagnosis

Comparative genomic hybridization (CGH)-based microarrays are now often used during pregnancy in case of fetal polymalformation in order to assess significant genomic alterations. Up to now, in case of isolated heart defect, only fetal karyotype with FISH 22q11 was usually offered. However, micro deletions or duplications could not be identified ...

Phase N/A

The Leiden Nonischemic Cardiomyopathy Study

Rationale: Sudden cardiac death, mainly caused by ventricular arrhythmias (VA), is a major cause of morbidity and mortality in non-ischemic cardiomyopathy (NICM). Therapies that effectively prevent VA are lacking. Improved understanding of the substrate and mechanisms of VA in NICM may allow more effective, individualized and substrate-based therapies to be ...

Phase N/A

Clinical and Genetic Examinations of Dilated Cardiomyopathy

Title Clinical and genetic examinations of dilated cardiomyopathy Background Dilated cardiomyopathy (DCM) is a severe disease of the heart muscle characterised by reduced pumping function and dilatation of the left ventricle without any obvious cause like hypertension, ischemic heart disease or heart valve disease. The patients often complain about shortness ...

Phase N/A

The Rhytmia System to Determine the Precise Location and Potential Mechanism of Premature Contractions

This is a purely observational study. No special methodology choice, no comparison. The study want to find the determination of precise location of the focus and mechanisms involved constitutes a challenge for conventional electrophysiology, even with tridimensional systems, because of the time needed for accurate delineation of the location (due ...

Phase N/A

Mental Imagery Therapy for Autism (MITA) - an Early Intervention Computerized Brain Training Program for Children With ASD

Visual puzzles have been used for centuries to facilitate early development in kids. Mental Imagery Therapy for Autism (MITA) is a unique, early-intervention application for children with Autism Spectrum Disorder (ASD). The app includes bright, interactive puzzles designed to help children learn how to mentally integrate multiple features of an ...

Phase N/A

Registry of Cell Therapy in Non-Ischemic Dilated Cardiomyopathy

Registry will include all patients who underwent intracoronary or intramyocardial cell therapy as a part of clinical trials performed at UMC Ljubljana from January 2005 until January 2018. Patients will be followed on regular basis in a dedicated heart failure outpatient clinic, clinical data will be collected and stored in ...

Phase N/A

NOACs for Atrial Tachyarrhythmias in Congenital Heart Disease

Rationale: Adult patients with congenital heart disease (CHD) with atrial tachyarrhythmias need to be anticoagulated. It is not known whether non-vitamin K antagonist oral anticoagulants (NOAC) in this patient group are efficient and safe. Aim: The purpose of the NOTE registry is to evaluate the efficacy and safety of NOACs ...

Phase N/A

Cardiac Function After Transcatheter VSD Closure

The investigators will enroll 50 consecutive patients with VSDs from the outpatient clinic of National Taiwan University Children's Hospital and Yi-Da Hospital. All participants will receive transcatheter VSD closure after comprehensive discussion with the clinical physicians and the performing clinicians. However, the investigators do not assign such treatment to the ...

Phase N/A

Stress Echo 2020 - The International Stress Echo Study

In a prospective, multicenter, international, observational study design, > 100 SE labs will be networked with systematic clinical, laboratory and imaging data collection at the time of SE and with structured follow-up information at least at 6 months and 1 year, up to 3 years for specific protocols. For all ...

Phase N/A