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Appendicitis Clinical Trials

A listing of Appendicitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (22) clinical trials

Trial on Postoperative Outcomes According to the Number of Trocar During Laparoscopic Appendectomy

Appendicitis is the most common benign inflammatory disease that requires an operation. Laparoscopic appendectomy using three trocar is generally performed, and reveals good surgical outcomes incluing less pain, early recovey, cosmetic effect et al. However, with using three trocar, there are some problems including pain around trocar insertion sites(three portions), ...


DIAgnostic iMaging or Observation in Early Equivocal appeNDicitis

For the study equivocal appendicitis is defined as clinical suspicion of appendicitis with Adult Appendicitis Score between 11 and 15. The estimated prevalence of appendicitis in such patients is around 50%. Diagnostic imaging is done using conditional computed tomography i.e. abdominal ultrasound first and computed tomography only after negative or ...

Phase N/A

Non-operative Management for Appendicitis in Children

Appendicectomy for acute appendicitis is one of the most commonly performed paediatric emergency operations in Australia. This standard treatment of acute uncomplicated appendicitis (AUA) has remained largely unchallenged since its introduction in the late nineteenth century, under the assumption that AUA progresses to perforation and thus complications should an operation ...

Phase N/A

Appendectomy Versus Non-Operative Treatment For Acute Non-Perforated Appendicitis in Children

Background Acute appendicitis is the commonest surgical emergency in children. The lifetime risk of developing appendicitis is 7-8%, with a peak incidence in the teenage years.The associated financial burden of treating appendicitis is very large. For over 100 years, surgical removal of the appendix has been deemed necessary to effectively ...

Phase N/A

Nebulized Analgesia for Laparoscopic Appendectomy Trial

The laparoscopic approach to pediatric appendectomy is gaining in popularity and has been demonstrated to reduce complications and improve resource utilization. The procedure has a documented association with high postoperative pain intensity, and is associated with substantial pain (pain scores >4 for >60% of the time) in 33% of patients. ...


Randomized Control Trial: Two Different Antibiotics Versus One Antibiotic for Pediatric Perforated Appendicitis

The diagnosis of perforated appendicitis will be documented intraoperatively with photos of extraluminal fecal contents or visible holes on the appendix. Patients will be randomized to 121 in each arm. Postoperative antibiotic therapy option will be decided based on blinded sequence model. 30 day postoperative follow up visit or calls ...

Phase N/A

A clinical trial seeking patients for a research study of Augmentin + Gentamicin

Initial non-operative treatment of acute simple appendicitis has recently been investigated in both the adult as the paediatric population. In the adult population, six Randomised Controlled Trial (RCTs) showed that an appendectomy could be avoided in 40-76% of the patients at the end of their follow-up period. Despite the fact ...


A Trial to Assess the Efficacy and Safety of Morinidazole in Patients With Appendicitis

Acute appendicitis is among the most common cause of acute abdominal pain. In patients with complicated acute appendicitis, postoperative, broad-spectrum antibiotics are always recommended. Metronidazole, a member of the nitroimidazole drug class, is included in the regimens recommended for improving anaerobic bacteria coverage. The sideeffects of metronidazole include a metallic ...


The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) Trial

The Comparison of Outcomes of Antibiotic Drugs and Appendectomy (CODA) trial aims to test, if from a patient's perspective, the antibiotics strategy is "just as good as" surgery. The investigators believe that patients, clinicians, and the people who pay for healthcare (both patients and insurers) will find the antibiotics approach ...

Phase N/A

Conservative Versus Operative ManageMent of Acute Uncomplicated Appendicitis

The study will include patients aged 16 and over, with a first admission with right iliac fossa pain and a raised white cell count or C-reactive protein. Patients will be randomised electronically in a 1:1 ratio either to undergo emergency appendectomy or to receive intravenous antibiotics as an inpatient, until ...