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Thyroid Cancer Clinical Trials

A listing of Thyroid Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (149) clinical trials

Trial of sorafenib versus placebo in the treatment of locally advanced or metastatic differentiated thyroid cancer refractory to radioiodine Eligible subjects were randomized 1:1 to sorafenib 800 mg daily or matching placebo. Progression was assessed every 8 weeks by modified RECIST criteria. Subjects had the option to unblind study treatment ...

Phase

Bioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic Malignancies

Stage I - Pharmacokinetics (Bioequivalence) Subjects will be randomized to receive CC-486 300 mg orally on each of the two pharmacokinetic (PK) study days based on the dosing sequences they are randomized to: Dosing Sequence 1: 2x150 mg tablets followed by 1x30 mg tablet. Dosing Sequence 2: 1x300 mg tablet ...

Phase

Study to Evaluate the Safety and Tolerability of Avelumab in Combination With Other Anti-Cancer Therapies in Patients With Advanced Malignancies

Arm A: Study Drug Administration: You will receive utomilumab by vein over 60 minutes on Day 1 of each 28-day study cycle. Starting on Day 1 of Cycle 3, you will receive avelumab by vein over 60 minutes on Days 1 and 15 of each cycle after that. You will ...

Phase

Levothyroxine Replacement With Liquid Gel Capsules vs Tablets Post-thyroidectomy

Ten patients will be randomized prior to surgery to receive levothyroxine in tablet form and ten patients will be randomized to receive in gel capsule form. Both forms will be encapsulated in order to allow double-blinding of the study. The postoperative goal TSH will be between 0.1 and 0.5 mU/L ...

Phase

Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery

This is a prospective randomized controlled study.In the experimental group, the suture parathyroid marker method was used to mark the parathyroid gland at the first time when it shows, and this marker was further used to identify and locating the inferior parathyroid marker in subsequent central region dissection. In the ...

Phase N/A

Comparison of Iodine-124 (I-124) and Iodine-131 (I-131) Radiopharmacokinetics in Patients Prepared With Recombinant Human TSH Injection (rhTSH)

Radiopharmacokinetics and Dosimetric Calculations A tracer dosage of either I-131 or I-124 is first administered to the patient, and the clearance is then followed for the specified period. In the classical approach, the blood is considered the critical organ which is irradiated either from the particles emitted from activity in ...

Phase N/A

Comparison of I-124 and I-131 Radiopharmacokinetics in DTC Patients With Thyroid Hormone Withdrawal

Radiopharmacokinetics and Dosimetric Calculations A tracer dosage of either I-131 or I-124 is first administered to the patient, and the clearance is then followed for the specified period. In the classical approach, the blood is considered the critical organ which is irradiated either from the particles emitted from activity in ...

Phase N/A

Phase 1 Study of the Highly-selective RET Inhibitor BLU-667 in Patients With Thyroid Cancer Non-Small Cell Lung Cancer and Other Advanced Solid Tumors

The study consists of 2 parts, a dose-escalation part (Part 1) and an expansion part (Part 2). Both parts will enroll patients with advanced NSCLC, advanced thyroid cancer and other advanced solid tumors that have progressed following standard systemic therapy, have not adequately responded to standard systemic therapy, or in ...

Phase

Study on the Application of Convenient Foot-control Exhaust Method in Endoscopic Thyroidectomy

The patients with papillary thyroid microcarcinoma were included according to the inclusive criteria and randomly divided them into two groups (foot-control exhaust group and direct exhaust group). The foot-control exhaust group used the foot-control exhaust method by the way of adjustable Pressure to intermittent exhaust, while direct exhaust group exhaust ...

Phase N/A

Thyroid Gland Removal With or Without Central Lymph Node Dissection in Treating Patients With Node Negative Thyroid Cancer

PRIMARY OBJECTIVES: I. To determine the rate of transient and permanent hypocalcemia SECONDARY OBJECTIVES: I. To determine the rate of voice and swallowing problems. II. To determine the degree to which quality of life (QOL) is compromised. III. To determine the degree to which accurate quality of life measures can ...

Phase