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Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (43) clinical trials

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT01794000?term=H7T-MC-TADO&rank=1

Phase N/A

What is the purpose of the HOPE study? The HOPE study will evaluate whether an investigational medication will be safe and effective in reducing anemia, pain crises, fatigue, and other day-to-day symptoms in adolescents and adults with SCD. An investigational medication means that it has not been approved for use ...

Phase N/A

Allogeneic SCT of CordIn in Patients With Hemoglobinopathies

CordIn™ is a cryopreserved stem/progenitor cell-based product of purified CD133+ cells composed of ex vivo expanded allogeneic UCB cells. The trial ends when the last patient completes their last visit. The overall study objectives are to evaluate the safety and efficacy of CordIn™: single ex-vivo expanded cord blood unit transplantation ...

Phase

Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD

This will be a phase II, multi-centre, randomized, double-blind, placebo-controlled study designed to assess preliminary efficacy, safety and pharmacokinetics (PK) of 2-7 days continuous IV administration of sevuparin for the management of acute VOC in subjects with SCD. Adults and adolescents ≥ 12 years of age will be randomized to ...

Phase

Efficacy and Safety of Ferriprox in Patients With Sickle Cell Disease or Other Anemias

Deferiprone (brand name Ferriprox®) is an iron chelator that is approved in the United States and over 60 other countries for the treatment of iron overload in patients with thalassemia, when other treatments are inadequate. This study has been designed to evaluate the efficacy, safety, and tolerability of deferiprone vs. ...

Phase

A Study Evaluating the Safety and Efficacy of the LentiGlobin BB305 Drug Product in Severe Sickle Cell Disease

Subject participation for this study will be 2 years post-transplant. Subjects who enroll in this study will be asked to participate in a subsequent long-term follow up study that will monitor the safety and efficacy of the treatment they receive for up to 13 years post-transplant.

Phase