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Neuroendocrine Carcinoma Clinical Trials

A listing of Neuroendocrine Carcinoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (17) clinical trials

A clinical trial to evaluate treatments for patients with Small Cell Lung Cancer

Phase III randomized clinical trial of lurbinectedin (PM01183)/doxorubicin (DOX) versus cyclophosphamide (CTX), doxorubicin (DOX) and vincristine (VCR) (CAV) or topotecan as treatment in patients with small-cell lung cancer (SCLC) who failed one prior platinum-containing line to determine a difference in progression-free survival (PFS) by an Independent Review Committee (IRC) between ...


A clinical research study of Durvalumab, Poly ICLC, Tremelimumab

This is an open-label, multicenter Phase 1/2 study of the CTLA-4 antibody, tremelimumab, and the PD-L1 antibody, durvalumab (MEDI4736), in combination with the tumor microenvironment (TME) modulator polyICLC, a TLR3 agonist, in subjects with advanced, measurable, biopsy-accessible cancers.


A clinical research study for the treatment of Bronchial Neoplasm, Small Cell Lung Cancer, Lung Neoplasm

Using Intensity Modulated radiotherapy it is possible to treat the entire brain to standard dosages of whole-brain radiation, while keeping the radiation dose to the hippocampus low. However, a clear relationship between radiation dose and damage to the hippocampal stem cells has not been established yet. This study is initiated ...


Patients are needed to participate in a clinical research study for the treatment of Carcinoma, skin cancer, Neuroendocrine Tumor, Adenocarcinoma, melanoma

BACKGROUND Patients receiving care at the NIH Clinical Center are required to be enrolled in a clinical protocol Following participation in a treatment protocol, it may be in the best interest of the patient to continue to be followed at the Clinical Center The NCI Surgery Branch conducts clinical trials ...

Phase N/A

A clinical research study of Pembrolizumab for the treatment of Neuroendocrine carcinoma, Neuroendocrine Tumor, Neuroendocrine Cancer

The purpose of this study is to: Assess overall radiographic response rate (ORR) Assess progression-free survival (PFS) Test the safety and tolerability of Pembrolizumab


A clinical trial seeking patients for a research study of Romidepsin

PRIMARY OBJECTIVES: I. To establish the safety and tolerability of romidepsin given on days 1, 8, and 15 of a 28 day cycle to patients with varying degrees of liver dysfunction (mild, moderate and severe). II. To establish the maximum tolerated dose (MTD) and appropriate dosing recommendations for romidepsin in ...


Patients are needed to participate in a clinical research study evaluating Carboplatin, Etoposide, Normal saline solution, Cisplatin for the treatment of Oat cell carcinoma, Small Cell Lung Cancer

The purpose of this study is to assess the safety and efficacy of pembrolizumab plus standard of care (SOC) chemotherapy (etoposide/platinum [EP]) in participants with newly diagnosed extensive stage small cell lung cancer (ES-SCLC) who have not previously received systemic therapy for this malignancy. The primary study hypotheses are that ...


A clinical trial seeking patients for a research study for the treatment of Non-Small Cell Lung Cancer, Small Cell Lung Cancer

This research study is a Phase I clinical trial, which tests the safety of an investigational intervention and also tries to define the appropriate dose of the investigational intervention to use for further studies. "Investigational" means that the intervention is being studied. The U.S. Food and Drug Administration (FDA) has ...

Phase N/A

A clinical trial seeking patients for a research study for the treatment of Islet Cell Tumor, Unresectable Solid Neoplasm, Fibrolamellar Carcinoma, Ovarian Cancer, Advanced Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Refractory Malignant Solid Neoplasm

PRIMARY OBJECTIVES: I. To evaluate safety and tolerability, determine maximum tolerated dose (MTD) and recommend a phase II dose of the combination of MLN0128 (TAK-228) (sapanisertib) with ziv-aflibercept in patients with advanced cancers refractory to standard therapy. SECONDARY OBJECTIVES: I. To give early indication of efficacy by evaluation of tumor ...