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Epilepsy Clinical Trials

A listing of Epilepsy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (7) clinical trials

Repeat-Dose Pharmacokinetics Study of NRL-1 in Epilepsy Subjects

Diazepam rectal gel (Diastat) is the only formulation of diazepam indicated for the management of selected, refractory patients with epilepsy on stable regimens of antiepileptic drugs (AEDs) who require intermittent use of diazepam to control bouts of increased seizure activity, i.e., Acute Repetitive Seizures (ARS). A diazepam nasal spray is ...

Phase

Bioavailability Safety and Tolerability of BIS-001 ER

This study investigates the safety, tolerability, and pharmacokinetics of BIS-001 ER in healthy volunteers. Subjects will be dosed twice daily, with a dose escalation occurring every 2-3 days until a maximum dose of 5mg per day is reached.

Phase

High Definition Cathodal Transcranial Direct Current Stimulation for Treatment of Refractory Partial Onset Epilepsy

1 Introduction This document is a protocol for a human research study. This study is to be conducted in accordance with US government research regulations, and applicable international standards of Good Clinical Practice, and institutional research policies and procedures. 1.1 Background Focal Status epilepticus (FSE) is characterized by a prolonged, ...

Phase

High Frequency Oscillations in Neurologic Disease

This study is designed to evaluate the high-frequency range deep brain oscillations (HFO) as pathologic markers in patients undergoing deep brain stimulation for epilepsy or Parkinson disease. Newly developed technology allows for the chronic recording of these brain signals at the same time as clinical stimulation is occuring. We will ...

Phase

University of Alabama at Birmingham (UAB) Adult CBD Program

The specific goals of this phase 1 dose finding study conducted in consecutively enrolled patients 15 years and older are to prospectively and longitudinally assess the safety and tolerability, including cognitive effects, of CBD at various doses between 5 mg/kg/day and 25 mg/kg/day with additional titration in some cases up ...

Phase

Safety and Tolerability of Epidiolex In Patients ((Ages 1 - 19 Years) With Intractable Epilepsy

The specific goals of this phase I dose finding study conducted in consecutively enrolled patients 1-18 years of age are to prospectively and longitudinally assess the safety and tolerability, including cognitive effects, of CBD at various doses between 5 mg/kg/day and 25 mg/kg/day with additional titration in some subjects up ...

Phase

Treatment Development of Triheptanoin (G1D)

The trial will use an open-label, standard 3+3 phase i design for determining the MTD of orally-administered C7 in G1D. Triheptanoin: a triglyceride oil containing three odd-carbon chain-length fatty acids (i.e., a triglyceride of 7-carbon heptanoic acid). Triheptanoin will be taken 4 times per day (approximately every 6 hours) by ...

Phase