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Pemphigus Vulgaris (PV) Clinical Trials

A listing of Pemphigus Vulgaris (PV) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (7) clinical trials

A Study to Evaluate the Efficacy and Safety of Rituximab Versus Mycophenolate Mofetil (MMF) in Participants With Pemphigus Vulgaris (PV)

This is a Phase III, randomized, double-blind, double-dummy, active-comparator, parallel-arm, multicenter study to evaluate the efficacy and safety of rituximab compared with MMF in participants with moderate-to-severely active PV requiring 60-120 milligrams per day (mg/day) oral prednisone or equivalent. Participants must have a confirmed diagnosis of PV within the previous ...


A Study of PRN1008 in Adult Patients With Pemphigus Vulgaris

Primary Objectives: To evaluate the safety of PRN1008 in patients with pemphigus vulgaris (PV) To evaluate the clinical activity of PRN1008 in patients with PV, per criteria in the European Academy of Dermatology and Venereology (EADV) 2014 Pemphigus S2 Guideline (Hertl et al. 2015) Secondary Objectives To evaluate the pharmacokinetics ...


Polyclonal Regulatory T Cells (PolyTregs) for Pemphigus

Up to 12 adults between the ages of 18 and 75 years of age who have been diagnosed with pemphigus and meet all other entry criteria will be enrolled to receive one infusion of their own expanded Tregs at one of the following doses: 2.5 x 10^8 PolyTregs or 10 ...


A Study to Evaluate the Safety PD PK and Efficacy of ARGX-113 in Patients With Pemphigus Vulgaris

The proposed study is an open-label, non-controlled, adaptive-design Phase II study to evaluate the safety, pharmacodynamics, pharmacokinetics, efficacy, and conditions of use (dosage, frequency of administration at maintenance) of ARGX-113 in patients with mild to moderate Pemphigus Vulgaris, either newly diagnosed or relapsing. The total study duration for each patient ...


A Safety Study of SYNT001 in Subjects With Pemphigus (Vulgaris or Foliaceus)

This study is being conducted to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), immunogenicity, and effects on pemphigus disease activity markers of intravenous (IV) SYNT001.


Autoimmune Blistering Diseases Study

The disease severity instruments for pemphigus and BP, the Pemphigus Disease Area Index (PDAI) and the Bullous Pemphigoid Disease Area Index (BPDAI), respectively, have the potential to capture changes in all grades of disease activity, including mild disease, and therefore represent a substantial improvement over simple lesion counts or measurements ...

Phase N/A

Identification of Vulnerability Factors in the Course of Pemphigus Patients

The originality of the project lies in its multidisciplinary approach (dermatology, psychology, sociology). No such study has yet been carried out in the pemphigus who has been the subject of a very small number of works in sociology or psychology. The only studies are studies of quality of life with ...

Phase N/A