Home » Clinical Trials »  Search Clinical Trials

Therapeutic Areas:  |  Urology

Search Medical Condition
Please enter condition
Please choose location

Urethral Strictures Clinical Trials

A listing of Urethral Strictures medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (8) clinical trials

Safety and Feasibility Study of Autologous Engineered Urethral Constructs for the Treatment of Strictures

This is a Phase I clinical study to determine the safety and efficacy of using autologous, engineered urethral constructs for the treatment of urethral strictures in adult males. The proposed study design is a prospective non-randomized and uncontrolled single-center investigation. Autologous urothelial cells (UCs) and smooth muscle cells (SMCs), obtained ...

Phase

Tissue-engineered Construct Based on Buccal Mucosa Cells and Matrix From Collagen and Polylactoglycolide Fibers

Treatment of urethral strictures longer than 2 cm is an actual clinical challenge. In this case, the common method is replacement surgery using a buccal mucosa graft. However, the main disadvantage of this method is associated with limited donor resources and donor site morbidity. The aim of this study is ...

Phase N/A

Re-establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

The study described below is designed to assess the safety and device performance for the drug coated balloon (DCB) for the treatment of urethral stricture.

Phase N/A

Functional Outcome of Urethral Reconstructive Surgery

Urethroplasty is the surgical repair of a urethral stricture. Depending on the location, severity and length of the stricture, various techniques can be performed. The first procedure consists of the excision of the stenotic segment and end-to-end anastomosis. Other procedures consist of widening the urethra with buccal mucosa as free ...

Phase N/A

ROBUST I Pilot Study

The study is designed to determine the safety and effectiveness for drug coated balloon (DCB). Up to 30 subjects will be enrolled and treated with the device at up to 3 clinical sites. Due to the significantly higher prevalence of strictures in men vs. women and the etiology of those ...

Phase N/A

A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty

Screening for eligibility; Enrollment/baseline: Patients are referred to UCSF urology clinic for urethroplasty. Participants commonly come to the clinic having already had imaging of their stricture, completed the appropriate PROMs, uroflowmetry and post-void residual urine volume measurement. The patient usually leaves the initial clinic visit with a scheduled surgery. Thus, ...

Phase N/A

Scandinavian Urethroplasty Study

The study is a prospective, randomized study to compare two common techniques of urethroplasty used to treat bulbar urethral strictures. One technique is excision of the stricture and end-to-end anastomosis of the urethra. The other technique is an onlay grafting procedure with buccal mucosa where the corpus spongiosum is not ...

Phase N/A

Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft

Urethral strictures affect 1% of men and are rare in women. Most urethral strictures in the United States develop in the bulbar section of the urethra which is the section of the urethra proximal to the penis but distal to the prostate. A common method of surgical correction is to ...

Phase N/A