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Diabetes Mellitus, Type 1 Clinical Trials

A listing of Diabetes Mellitus, Type 1 medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (130) clinical trials

Prevalence of Obstructive Sleep Apnea Syndrome in Type 1 Diabetic Patients Treated With Insulin Pump (At1Home)

Patients with type 1 diabetes have poorer glycemic control that could lead to macrovascular or neuropathic complications; in addition to an optimal treatment, prevention of diabetes complications requires to control associated risk factors, such as hypertension or dyslipidemia. Sleep apnea syndrome is a public health problem due to its high ...

Phase N/A

Immune Profile in Subjects With New Onset Type 1 Diabetes

It is hypothesized that early changes in the immune system in New Onset Type 1 Diabetes Mellitus (NOT1D) subjects can be detected in immune cells from the inguinal lymph nodes (iLN), which will be distinct from changes observed in peripheral blood derived immune cells. Therefore this study will assess and ...

Phase N/A

A Phase 2 Multicentre Randomized Double-blind Placebo-controlled Study in Patients With New-onset Type 1 Diabetes

T1D is an organ-specific autoimmune disease in which the immune system attacks the insulin-producing β-cells. The onset of the disease typically occurs before adulthood and seriously affects a person's quality of life. T1D is treated with life-long daily exogenous insulin injections and monitoring of blood glucose levels. However, even optimization ...


Neuropeptide Therapy of Recent Onset Type 1 Diabetes

This study evaluates the delivery of substance P via the celiac artery in the treatment of recent onset type 1 diabetes.


International Diabetes Closed Loop (iDCL) Trial: Research Site Training Protocol

Participation in this study will require 5 study visits over 2-4 weeks. - Visit 1: screening/enrollment visit to assess study eligibility. - Visit 2: continuous glucose monitor (CGM) training and initiation session based upon current or prior use of a CGM; if subject doesn't currently use a CGM, subject will ...

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A Study of SIMPONI to Arrest Beta-cell Loss in Type 1 Diabetes

The primary purpose of this study is to determine if golimumab can preserve beta-cell function in children and young adults with newly diagnosed Type 1 Diabetes (T1D).


A Pilot Study of Nocturnal Hypoglycemia Prevention in Type 1 Diabetes Using the Vigilant Diabetes Management Companion

This is a pilot study to determine whether a large-scale randomized trial is feasible. The pilot study will test if the Vigilant Diabetes Management System is effective in adults with T-I Diabetes in preventing nocturnal hypoglycemia, improving moderate hypoglycemia, improving diabetes quality of life and in reducing fear of hypoglycemia. ...

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A Study to Demonstrate Bioequivalence Between Insulin Glulisine U300 and Insulin Glulisine U100 After a Single Subcutaneous Dose Using the Euglycemic Clamp Technique in Patients With Type 1 Diabetes Mellitus

The study duration per patient will be 18 to 62 days and will consist of a 4 to 28 days of screening period, a treatment period of 2 days, a washout between dosing occasions of 5-18 days, and follow up visit 7-14 days after last dosing.


Evaluation of the Hypoglycaemia Alarm Device Hyposafe H02

To evaluate the technical performance of the hyposafe H02 during everyday activities and during insulin-induced hypoglycaemia, in addition to safety issues associated with the implantation and use of the hyposafe H02 in subjects with type 1 diabetes.

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A Study of LY3209590 in Healthy Participants and Participants With Type 2 Diabetes

This trial is conducted to evaluate the safety of a study drug given by injection under the skin to healthy participants and participants with type 2 diabetes. It will also investigate how the body processes the study drug and the effect of the study drug on blood sugar levels. Information ...