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Lymphedema Clinical Trials

A listing of Lymphedema medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (9) clinical trials

For more information please visit: http://clinicaltrials.gov/ct2/show/NCT00956670?term=GOG+0244&rank=1

Phase N/A

Bioimpedance Spectroscopy Versus Tape Measure in Prevention of Lymphedema

The treatment of lymphedema following breast cancer therapy is typically a burdensome multi-modality process that entails different degrees of intensity depending on the severity of fluid accumulation. In breast cancer survivors, it is most commonly initiated after visible swelling occurs in a limb. Common treatments utilized are multi-modality and include ...

Phase N/A

Quality of Life Changes on Lower Extremity Lymphedema Patients Using an Advanced PCD

Multi-centered, single arm, observational clinical trial of a prospective cohort of an estimated 300 participants with primary or secondary, unilateral or bilateral, lower extremity lymphedema. All participants receive intermittent pneumatic compression treatment for 52 weeks. Quality of life and symptoms will be assessed pre- and post - intermittent pneumatic compression ...

Phase N/A

Ubenimex in Adult Patients With Lymphedema of The Lower Limb (ULTRA)

Leukotriene B4 (LTB4) inhibits lymphangiogenesis in the mouse tail model of lymphedema and is elevated in tissue in patients with lymphedema. Ubenimex is an inhibitor of leukotriene A4 hydrolase (LTA4H), the biosynthetic enzyme for LTB4. This proof-of-concept study is designed as a randomized, double-blind, placebo-controlled study comparing ubenimex at 150 ...

Phase

Lymphedema Prophylaxis in Breast Cancer Survivors Who Show Early Evidence of High-risk Status

The current investigation is designed to prospectively evaluate the potential for simple, effective lymphedema prophylaxis in breast cancer survivors who show early evidence of high-risk status. There is growing evidence that the mechanisms of lymphatic repair after injury are mediated through lymphatic flow. Accordingly, we propose that physical measures designed ...

Phase N/A

Treatment of Lymphedema: Application of the Kinesio Taping

First part: To investigate the reliability study of water displacement and circumference measurement and the change in thickness of subcutaneous space measured by sonography and blood flow measured by DRT4 in normal subjects after applying K-tape. Second part: The incidence of breast carcinoma is in the second place in women ...

Phase

Response to Intermittent Pneumatic Compression Therapy in Head and Neck Cancer-related Lymphedema

A non-randomized, non-blinded, single site pilot study designed to assess whether near-infrared fluorescence imaging can report on the efficacy of a pneumatic compression device to move lymph in head and neck cancer survivors with resulting head and neck lymphedema.

Phase

A Phase I Study With Lymfactin in the Treatment of Patients With Secondary Lymphedema

This is an open label, multi-center, uncontrolled first in human trial that uses a standard 3 + 3 dose escalation scheme. Lymfactin® will be administered as a single dose by ex vivo perinodal injection into the fat pad of a flap of tissue containing lymph nodes from the abdominal wall. ...

Phase

Two Pneumatic Compression Devices in the Treatment of Lower Extremity Lymphedema

This is a Multicentre, prospective, single (assessor) blind randomised study. The primary objective of the study is to assess volume reduction in the treatment of lymphoedematous legs with an advanced PCD compared to a simple PCD in patients with lower limb lymphoedema. The main outcome is the percentage volume reduction ...

Phase