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Brain Injury Clinical Trials

A listing of Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (312) clinical trials

Brain Machine Interface (BMI) in Subjects Living With Quadriplegia

Medical device manufacturer Medtronic has developed a fully-implantable, bi-directional neuroprosthetic that is built upon existing deep brain stimulation (DBS) technology and has the ability to perform electrocorticogram recording and deliver functional electrical stimulation. This device is an incremental improvement to an existing Premarket Approved (PMA) deep brain stimulation (DBS) device ...

Phase N/A

Development of a Neurocognitive Screening Test

This research study will evaluate a standalone software application and is designed to standardize and validate new neurocognitive screening testing for children aged 6 through 11, and adolescents and adults ages 12 through 75. The purpose of this study is to evaluate recently developed computerized tasks sensitive to changes in ...

Phase N/A

ImPACT Normative Extension

The researchers want to find out more about a standalone software application, ImPACT Online and how it relates to other commonly used tests of memory, attention and reaction time. ImPACT Online is a computer-based neurocognitive test for concussion management. The test was designed to help measure the effects of concussion ...

Phase N/A

PAEAN - Erythropoietin for Hypoxic Ischaemic Encephalopathy in Newborns

A lack of oxygen (hypoxia) or low blood supply (ischaemia) before or during birth can destroy cells in a newborn baby's brain. The damage caused by the lack of oxygen continues for some time afterwards. One way to try to reduce this damage is to induce hypothermia cooling the baby ...

Phase

Rehabilitation of Working Memory and Brain Plasticity After Traumatic Brain Injury: Plastim-MDTC

This is a pilot feasibility study. Patients with subacute/chronic (> 6 months) severe TBI will be included if they suffer from a deficit in working memory. They will receive a specific hierarchical training of working memory (3 sessions per week during three months), according to a previously described methodology. A ...

Phase N/A

Mindfulness and Yoga Training for Athletes With Concussion (MYTAC)

Athletes and patients aged 15 - 60 will receive standard sports concussion evaluations at the Duke Sports Science Institute (SSI) and will learn about the study by the primary clinicians evaluating sports concussion at the SSI. Subjects will receive yoga training either at their home or at the Center for ...

Phase N/A

The Effectiveness of Biofeedback for Individuals With Long-term Post-concussive Symptoms

40% of minor head injuries are diagnosed with post-concussion syndrome 3 months after injury (Ingebrigtsen, Waterloo, Marup-Jensen, Attner, & Romner, 1998). These individuals have persistent symptoms after completing conventional rehabilitation programs. Persistent post-concussion symptoms not only decrease quality of life (Ingebrigtsen et al, 1998), but also impair cognitive and motor ...

Phase N/A

Impact of Early Optimization of Brain Oxygenation on Neurological Outcome After Severe Traumatic Brain Injury

Post-traumatic brain hypoxia/ischemia develops hours after traumatic brain injury (TBI), and its intensity is directly related to the neurological outcome. The thresholds for irreversible tissue damage following TBI indicate a particular vulnerability of injured brain. Improving brain oxygenation after severe TBI is the focus of modern TBI management in the ...

Phase N/A

Metacognitive Training to Enhance Strategy Use in Blast-Related TBI

OBJECTIVES Aim 1: is to test benefits of GMT for improving executive function. Aim 2: Investigate factors which affect response to treatment. RESEARCH PLAN: This is a randomized controlled study to investigate the effect of Goal Management Training (GMT) for those with blast-related mTBI. The control group will participate in ...

Phase N/A

CPPopt Guided Therapy: Assessment of Target Effectiveness

Despite improvements in management, mortality in severe traumatic brain injury (TBI) remains 25% and only 40% of patients survive without major handicap. Medical/surgical interventions aim to maintain adequate brain perfusion, which is critically dependent on cerebral perfusion pressure (CPP); calculated as the difference between mean arterial pressure (MAP) and intracranial ...

Phase N/A