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Brain Injury Clinical Trials

A listing of Brain Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (439) clinical trials

BrainGate2: Feasibility Study of an Intracortical Neural Interface System for Persons With Tetraplegia

The goal of the BrainGate2 research and development project is to identify the core methods and features for a medical device that could allow people with paralysis to recover a host of abilities that normally rely on the hands.

Phase N/A

TIBOHCA: Safety Tolerability and Pharmacokinetics of 2-Iminobiotin (2-IB) After OHCA

Objective The primary objective of this study is to evaluate the short term safety and tolerability, and the pharmacokinetic properties of 2-IB when administered to adult patients after OHCA. Study design: A Phase 2, single-centre, open-label, dose-escalation intervention study. Study population: The study population will constitute of three cohorts of ...

Phase

Use of Neurofeedback to Enhance Attention After Brain Injury

Participants taking part in the neurofeedback group will undertake sixteen 30-minute sessions of neurofeedback training, from Tuesday to Friday, distributed over the course of four weeks. Sessions will be performed at the same time each day. Each 30-min NFB session will consist of 7 x 3-minute blocks of training flanked ...

Phase N/A

Intra-operative Feed Back on Traction Force During Vacuum Extraction: Safe Vacuum Extraction Alliance

The most common indications for vacuum extraction are dystocia and/or fetal asphyxia. The safety of assisted vaginal delivery with vacuum extraction has been discussed since its introduction almost fifty years ago. Serious complications such as asphyxia, intracranial hemorrhage and seizures are overrepresented at vacuum extraction compared to spontaneous vaginal delivery. ...

Phase N/A

Myoelectric Upper Limb Orthosis Use by Persons With Traumatic Brain Injury

This study has two aims: (1) to evaluate therapeutic and neuroplastic effects of a myoelectric upper limb orthosis and (2) to evaluate the functional effects of a myoelectric upper limb orthosis. The investigators plan to recruit 15 Veterans and non-veterans who have Traumatic Brain Injury (TBI) and upper limb impairment, ...

Phase N/A

Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI

This research aims to develop an intervention that combines mTBI-specific motor and cognitive challenges into a progressive and challenging rehabilitation program. We plan to develop and refine a combined motor and cognitive intervention using healthy athletic young adults (n=12) and people with a positive history of non-resolving mTBI (n=12). We ...

Phase N/A

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study

Cognitive skills are the crucial abilities required to manage money, maintain employment, and live independently. Long-term cognitive impairment (LTCI) is a disabling loss of these skills that can persist for months to years. LTCI frequently occurs after primary brain injury (e.g., traumatic brain injury, hypoxia), but older LTCI research has ...

Phase N/A

Improving Ambulatory Community Access After Paralysis

In a surgical procedure electrodes are inserted into muscles of the lower extremities to correct hip, knee and ankle function. The electrode leads are connected to an implanted pulse generator located in the abdomen. After a typical post-operative period of two to five days, the recipient will be discharged home ...

Phase

Influence of Respiratory Gases Conditioning on Aerosol Delivery During Invasive Ventilation

The intention is to enroll a specific sample of intubated patients. To compare the effect of respiratory gas conditioning on lung deposition and considering the well-known influences of lung pathology on lung deposition, intubated patients with healthy lungs will be included. Postoperative neurosurgery ventilated patients respond perfectly to this criteria. ...

Phase N/A

LEAP a New Overground Body Weight Support Robot: Usability Trial

People with central nervous system disorders such as spinal cord injury, stroke, cerebral palsy, Parkinson's disease, multiple sclerosis, etc often have impaired lower extremity function that limits activities of daily life and independence. Different body-weight support systems have been developed to facilitate the rehabilitation process by compensating for the user's ...

Phase N/A