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Brain Tumor Clinical Trials

A listing of Brain Tumor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (537) clinical trials

Trial of Hypofractionated Radiation Therapy for Glioblastoma

Hypofractionated radiation therapy (RT) in the treatment of patients with glioblastoma, 18 - 70 years of age with good performance status (ECOG 0 - 2), will be well tolerated and yield survival non-inferior to conventional fractioned RT, allowing significant abbreviation of the length of the radiation course required for these ...

Phase

Evaluating Therapeutic Response to Novo-TTF

The patient is being asked to have 4 MRI scans of their brain over the course of 6 months. Before the patient can participate in the study a negative urine pregnancy test may be required for women of child-bearing age. Each MRI scan will take approximately 1 hour to complete. ...

Phase N/A

ERC1671/GM-CSF/Cyclophosphamide for the Treatment of Glioblastoma Multiforme

PRIMARY OBJECTIVES: The primary objective of the study is to determine the 6-month progression free survival probability of patients with recurrent, bevacizumab nave glioblastoma multiforme treated with ERC1671 in combination with GM-CSF and cyclophosphamide plus bevacizumab as compared with patients receiving bevacizumab plus placebo controls. SECONDARY OBJECTIVES: To evaluate radiographic ...

Phase

Clinical Development of Cancer-Specific MRS Biomarkers in Malignant Gliomas

Malignant gliomas represent the majority of primary brain tumors in adults and are among the most intractable tumors. Cancers reprogram their metabolism to meet the needs of rapid cell growth. Alterations in metabolite abundance may serve as biomarkers of malignancy, and the capability to monitor the changes non-invasively would have ...

Phase N/A

Prevention of Thrombocytopenia in Glioblastoma Patients

Chemotherapy used in the treatment of primitive tumors of the central nervous system has a particularly important platelet toxicity compared to chemotherapy used for treatment of other tumors. Chemotherapy postponed for toxicity is often due to thrombocytopenia (TP). The TP and/or the other anomalies of coagulation, which can be spontaneous ...

Phase

Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme

PRIMARY OBJECTIVES: I. To determine the accuracy of dose delivery and patient comfort with treatment time. II. To evaluate normal tissue dose volume statistics and compare to standard planning. OUTLINE Patients undergo 4pi radiation simulation and planning followed by 5 to 10 daily fractions of 4pi palliative radiotherapy. If an ...

Phase N/A

Tryptophan Metabolism in Human Brain Tumors

If you agree to take part in this research study, you will be asked to have: a PET scan, 2. brief clinical questionnaires, and 3. biochemical studies of blood and tumor tissue. You may also have a second PET scan later, if you undergo therapy (such as surgery and/or brain ...

Phase N/A

Trial Evaluating an Enhanced Physical Activity Intervention to Improve Cognitive Late Effects in Children Treated With Cranial Radiation for Brain Tumors

BACKGROUND Children treated with cranial radiation therapy (CRT) for brain tumors are at high risk for developing neurocognitive late effects consisting of significant declines in overall IQ and specific cognitive impairments, particularly in attention, memory, and processing speed. Academic functioning, daily activities, and quality of life (QOL) also are impacted, ...

Phase

Cerebellar Mutism Syndrome Study

Background Cancer accounts for 22 % of all deaths among children in Europe and is thus the leading non-traumatic pediatric cause of death. Central nervous system (CNS) tumours constitute 25% of all childhood cancers, and the majority of these are located in the posterior fossa. One of the most troublesome ...

Phase N/A

ALA-induced PpIX Fluorescence During Brain Tumor Resection

Removing a tumor from a patients brain is hard to do because, very often, brain tumors do not have boundaries that are easy for the patients surgeon to find. In many cases, the surgeon can't tell exactly where the tumor begins or ends. The surgeon usually can remove most of ...

Phase