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Dystonias Clinical Trials

A listing of Dystonias medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (73) clinical trials

Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The primary focal dystonias are the most common type of dystonia and include Limb dystonias (like writer's cramp), Cervical dystonia (spasmodic torticollis), Laryngeal dystonias (like spasmodic dysphonia), and Craniofacial dystonias (like blepharospasm). The purpose ...

Phase N/A

You are being asked to participate in this research study because you have cervical dystonia (CD). Botulinum toxin treatment can be offered as a treatment option for the treatment of CD. The current practice for botulinum toxin injection treatment is to inject patients every 3 months. However, not all patients ...

Phase

Assessment of Brain Activities in Cervical Dystonia

To address joint position sense in cervical dystonia patients and how it affects the brain activity.

Phase N/A

Dystonia Genotype-Phenotype Correlation

Identify a cohort of individuals with known dystonia-related gene mutations, and individuals with idiopathic but presumed-genetic dystonia. Some of these individuals may receive botulinum toxin injections to treat their dystonia per standard of care; in these patients, investigators will image before and after injections to assess for imaging correlates of ...

Phase N/A

Imaging Blood Brain Imaging Dysfunction in Parkinson's Disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder of aging. Its cause is unknown. Current evidence supports a stress-diathesis model of pathogenesis whereby some yet-to-be identified environmental trigger conspires with a permissive genetic background to initiate the disease process. Based on neuropathological observations in other neurodegenerative diseases, such ...

Phase N/A

Safety and Tolerability of Perampanel in Cervical Dystonia

Idiopathic cervical dystonia (CD) is the most common form of focal dystonia with a prevalence of approximately 60 cases per million population.(Nutt et al.,1988). Current oral medical treatments for CD have variable efficacy and often with marked side effects. Botulinum toxin injections may be more effective than pharmacological therapies, and ...

Phase

Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease

A patient's participation in the study will last for ten months and will include sixteen to seventeen visits: Screening (2 visits) Planning of surgery - Surgery: implantation of drug delivery system - Post-surgery follow-up (3 visits) Test infusions with vehicle (1-2 visits) Positron emission tomography (PET) examinations before the first ...

Phase

Effect of tDCS on Cognition Symptoms in Chronic Schizophrenia Patients With Tardive Dyskinesia

This study is a randomized, double-blind, sham-controlled clinical trial. 60 patients with TD were randomly allocated to active (n=30) or sham tDCS groups (n=30). All patients received 2-mA anodal left/cathodal right prefrontal tDCS treatment (fifteen 30-minutes sessions: Monday to Friday once daily, every other week to do a group of ...

Phase N/A

Proprioception and Meditation

In past work is has been shown that yoga can be as effective as a standard balance or Tai Chi protocol; however, there is an inability to distinguish between the mind and body contributions of yoga training. This study will compare an accepted proprioceptive training program to a meditation program ...

Phase N/A

ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders

The purpose of this study is to evaluate the safety and initial effectiveness of MRI-guided focused ultrasound thermal ablation of a designated area in the brain of patients suffering from movement disorder symptoms: FUS under MRI-guidance and MRI-based thermometry can be safely delivered to patients suffering from treatment-refractory movement disorders ...

Phase N/A