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Biliary Tract Cancer Clinical Trials

A listing of Biliary Tract Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (27) clinical trials

Biliary Tissue Sampling Using a Cytology Brush or the GIUM Catheter

Introduction Many patients with a suspected malignant biliary obstruction are considered unsuitable for surgery because of locally advanced or metastatic disease or poor clinical performance status. Management of these patients is facilitated by a tissue diagnosis at initial endoscopic retrograde cholangio-pancreatography (ERCP). This may obviate further invasive tests, and the ...

Phase

Study of Sulfatinib as Second-line Treatment in Patients With Biliary Tract Carcinoma

This study adopt Simon's two-stage designs method based on the primary endpoint of 16-week PFS rates. In the first stage, 16 patients will be accrued. If there are 3 or fewer patients without progression or death in these 16 patients at week 16, the study will be stopped. Otherwise, 16 ...

Phase

A Study of Merestinib (LY2801653) in Japanese Participants With Advanced or Metastatic Cancer

The main purpose of this study is to evaluate tolerability of merestinib monotherapy or in combination with other anti-cancer agents in Japanese participants with advanced and/or metastatic cancer.

Phase

An Open-Label Safety and Tolerability Study of INCB062079 in Subjects With Advanced Hepatocellular Carcinoma and Other Malignancies

The purpose of this study is to evaluate the safety and tolerability, and determine the maximum tolerated dose of INCB062079 in subjects with advanced hepatocellular carcinoma and other malignancies.

Phase

Apatinib as Second Line Therapy in Patients With Advanced Refractory Biliary Tract Cancers

Biliary tract cancers (BTC) includes cholangiocarcinoma and gallbladder carcinoma (GBC). The systematic treatment based on gemcitabine plus cisplatin is recommended as the current standard chemotherapy for unresectable or metastatic BTC. There is no standard recommendation for second line therapy. Apatinib is a tyrosine kinase inhibitor targeting vascular endothelial growth factor ...

Phase

PROCLAIM-CX-2009: A Trial to Find Safe and Active Doses of an Investigational Drug CX-2009 for Patients With Selected Solid Tumors

The purpose of this first-in-human study of CX-2009 is to characterize the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD) and antitumor activity of CX-2009 in adult subjects with metastatic or locally advanced unresectable solid tumors. PROCLAIM: PRObody CLinical Assessment In Man CX-2009 clinical trial 001 PROBODY is a trademark of CytomX ...

Phase

Phase 1/2 Study of LOXO-195 in Patients With Previously Treated NTRK Fusions or Non-fusion NTRK Cancers

The trial will be conducted in 2 parts: dose escalation (Phase I ) and dose expansion (Phase 2) . During Phase 1, patients with advanced solid tumors are eligible if the tumor has progressed following or has not adequately responded to standard therapy, or if the patient is intolerant of, ...

Phase