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Dyskinesias Clinical Trials

A listing of Dyskinesias medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (20) clinical trials

Phenotype/Genotype Correlations in Movement Disorders

Objective: The goal of this protocol is to identify families with inherited movement disorders and evaluate disease manifestations to establish an accurate clinical diagnosis, and to investigate the underlying molecular mechanisms. Studies of inherited movement disorders in large families with good genealogical records are especially valuable. Additionally, the plan is ...

Phase N/A

Bilateral Pallidal Stimulation in Patients With Advanced Parkinson's Disease-LATESTIM

The indication and excellent therapeutic effects of STN stimulation have been sufficiently proven in advanced PD, and the contraindications for this treatment are rather well established. Also, the observation that patients fulfilling the "STN-profile" but who had been operated for pallidal DBS and lost part of the treatment's benefit over ...

Phase N/A

Biomarker for Creatine Deficiency Syndromes

The creatine deficiency syndromes (CDS) are a group of inborn errors of metabolism which interrupt the biosynthesis or transportation of creatine. Individuals with creatine deficiency syndromes classically present with intellectual disabilities and seizure disorders and may present with pyramidal/extrapyramidal neurologic findings and behavioral problems as well. There are three Cerebral ...

Phase N/A

Safety and Efficacy Study of VY-AADC01 for Advanced Parkinson's Disease

Parkinson's disease (PD) is a neurodegenerative disorder involving loss of dopamine producing neurons located in the striatum. Levodopa is the primary treatment used to treat Parkinson's disease, which converts to dopamine by the enzyme (protein) Aromatic L-Amino Acid Decarboxylase (AADC). As PD progresses, the amount of AADC levels in the ...

Phase

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

A global, multi-center, open-label, observational registry to capture safety and effectiveness data related to ExAblate Neuro, an MRI guided focused ultrasound device designed to lesion tissue deep within the brain using sound waves without the need for craniotomy. This registry includes certain regional and country specific approved thalamotomy and pallidotomy ...

Phase N/A

Clinical Study to Test the Safety of CDNF by Brain Infusion in Patients With Parkinson's Disease

A patient's participation in the study will last for ten months and will include eighteen to nineteen visits: - Screening (2 visits) - Planning of surgery - Surgery: implantation of drug delivery system - Post-surgery follow-up (3 visits) - Test infusions with a contrast medium (gadolinium) (3 visits) - Positron ...

Phase