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Macular Edema Clinical Trials

A listing of Macular Edema medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (96) clinical trials

Efficacy and Tolerance Comparison Between Subconjunctival Injection of Triamcinolone and Intravitreal Implant of Dexamethasone for the Treatment of Inflammatory Macular Edema

This research compares the implantation techniques of corticosteroids in the eye, with two groups of equal size being followed. This is a multi-center, controlled study, with the reference drug being the intravitreal implant of 700g of dexamethasone (Ozurdex) compared to subconjunctival injection of triamcinolone (Knacort retard). This is an open, ...

Phase

OCT-angiography in Diabetic Patients

Patients who participate in this study will be selected among adults treated at the Retina Clinic and Ocular Oftalmologia clinics and will be aware of all stages of the research, formalizing the approval of their participation by informed consent term. The tests will be performed after pupillary dilation with 2 ...

Phase N/A

The Relationship Between Intraocular Pressure and Macular Edema in Patients With Diabetic Macular Edema

Ocular perfusion pressure (ocular perfusion pressure - OPP), considered the driving force of ocular blood flow. Perfusion pressure is defined as the difference between the artery and vein blood pressure. Because ocular venous pressure is the same or slightly higher than the IOP (intra ocular pressure - IOP), it is ...

Phase N/A

Conbercept Ophthalmic Injection for Patients With Macular Edema Caused by Branch Retinal Vein Occlusion

The purpose of this study is to verify the efficacy and safety of intravitreal injection of conbercept in patients with macular edema (ME) caused by branch retinal vein occlusion (BRVO).

Phase

Diabetic Retinopathy Assessed by Ultra-wide

Diabetic retinopathy imaged by ultra wide field angiography (200): the California (Optos, Scotland) allows ultrawide field pictures of 200 of the retina. This new imaging allows seeing beyond what was seen by the classic 7 ETDRS fields angiography: In pivotal studies assessing the effect of antiVEGFs on diabetic retinopathy (DR) ...

Phase N/A

Trial of Switching Between Intravitreal Bevacizumab (Avastin )& Intravitreal Dexamethasone (Ozurdex ) for Persistent Diabetic Macular Oedema

A Multicentre Clinical Trial of Switching Between Intravitreal Bevacizumab (Avastin) and Intravitreal Dexamethasone (Ozurdex) for Persistent Diabetic Macular Oedema (SwitchDMO)

Phase

Influence of Diabetes Control on Treatment of Diabetic Macular Edema With Ranibizumab

Patints with diabetic macular edema (DME) will be treated with intravitreal ranibizumab injections and the effect of optimal control of internal factors (eg. glycemia, blood presure etc) on final functional (best corrected visual acuity-CBVA) and morphological (central retinal thickness-CRT) will be investigated. Patients will be randomized into two groups: Group ...

Phase

Effect of Aflibercept (Eylea ) in the Management of Bevacizumab (Avastin ) Resistant Diabetic Macular Edema

In this study patients recruitment, clinical care and follow-up will be conducted by: Dr Flavio Rezende: Principal-Investigator and Dr Radwan Ajlan: Co-Investigator. Purpose: To evaluate the visual acuity outcomes and macular changes at 6 and 12 months of intravitreal aflibercept (2.0 mg) in eyes with persistent center involved diabetic macular ...

Phase

Phase I/II Trial to Find Maximum Tolerated Dose (MTD) and Dose Limiting Toxicities (DLT) of TLC399 (ProDex) in Patients With Macular Edema Due to Retinal Vein Occlusion (RVO)

This study will consist of 2 parts: Part 1 is an open-label, sequential dose escalation part to determine the Dose Limiting Toxicities (DLTs) and Maximum Tolerated Dose (MTD) of TLC399 (ProDex) in patients with macular edema due to central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO). Part ...

Phase

Treat-and-extend Regimen of Aflibercept in Diabetic Macular Edema (VIBIM Study)

Efficacy of aflibercept for diabetic macular edema was demonstrated in the phase III, VIVID and VISTA studies. In these studies, aflibercept was injected using the fixed dosing regimen that an intravitreal injection was performed 5 times every 4 weeks and then every 8 weeks. Although the efficacy was comparable to ...

Phase