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Recurrent Respiratory Papillomatosis Clinical Trials

A listing of Recurrent Respiratory Papillomatosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (5) clinical trials

Bevacizumab Versus Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis

The investigators designed a randomized, double-blind, placebo-controlled study. Children and adults will be randomized to receive either 3 dosis of intralesional bevacizumab, cidofovir or saline solution. Primary endpoints are the assessment of changes in the annual surgery rate and Derkay papilloma severity grading scale; secondary endpoints are changes in the ...


Pembrolizumab for HPV-associated Recurrent Respiratory Papilloma Patients With Laryngeal Tracheal and/or Pulmonary Involvement

This research study is a Phase II clinical trial. Phase II clinical trials test the safety and effectiveness of an investigational intervention to learn whether the intervention works in treating a specific disease. The FDA (the U.S. Food and Drug Administration) has not approved Pembrolizumab for your specific disease but ...


Recurrent Respiratory Papillomatosis and Extraesophageal Reflux

Recurrent respiratory papillomatosis (RRP) is a chronic viral disease, which affects children and adults as well. It is characterised by grow of squamous cell tumours on mucosa of aerodigestive tract, with predilection for the larynx. The disease is caused by the human papillomavirus (HPV). However, in contrast to the low ...

Phase N/A

Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP)

Primary aim: The overall goal is to improve the care of children with Recurrent Respiratory Papillomatosis (RRP) - and the investigators aim to do this by determining the most effective and safe RRP treatments currently being used in paediatric patients in National Health Service (NHS) hospitals within the United Kingdom ...

Phase N/A

M7824 in People With Recurrent Respiratory Papillomatosis

Background Recurrent respiratory papillomatosis (RRP) is a rare papillomatous disease of the aerodigestive tract that is caused by the Human Papilloma Virus (HPV). RRP can progress to cause airway compromise, fatal pulmonary lesions, and invasive cancers. There is no effective systemic therapy for RRP. Patients typically require repeated interventional procedures ...