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Anesthesia (Local) Clinical Trials

A listing of Anesthesia (Local) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (90) clinical trials

Effectiveness of Buccal Infiltration During Vital Pulpotomy After Administering Two Analgesic Premedications

A total of 60 healthy children will be recruited from the outpatient clinic of the Pediatric Dentistry and Dental Public Health Department, Faculty of Dentistry, Ain Shams University. Inclusion Criteria include: age group 7-9 years Without systemic or mental disorders. Who could be categorized as cooperative according to Wright's classification ...

Phase N/A

A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade

Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia. The primary objective of this study is to evaluate the systemic and local safety and tolerability of ascending doses of neosaxitoxin alone and in combination with fixed doses of bupivacaine (with ...


Treatment Prior to Injection and Biopsy of the Vulva

To diagnose skin conditions of the vulva and determine appropriate treatment, a biopsy is often taken as an outpatient procedure. Prior to biopsy, the skin is cleansed and injected with a numbing solution. These injections can be quite painful in this sensitive area. Ice has been used as topical anesthesia ...

Phase N/A

Efficacy and Safety of Electric Stimulation-guided Epidural Anesthesia for Cesarean Section

Investigators will place epidural catheter in the epidural space using loss of resistance technique, and will confirm correct placement of the epidural catheter using electric stimulation. Epidural catheter placement, electric stimulation, and confirmation of response is followed: Patients will be placed in the left lateral decubitus position. The site will ...

Phase N/A

Effect of the DentalVibe Injection System on Pain During Local Anesthesia Injections in Children

Up to 50 children between the ages of 5-11 years will participate in this randomized, controlled, split-mouth study. There will be no gender restrictions used in this study. Participants will be recruited from a continuous sample of patient seen at the UNMC pediatric dental clinic and will be selected based ...

Phase N/A

A clinical trial seeking patients for a research study for the treatment of Ankle Fracture Surgery, Chronic Pain, Regional anesthesia

This pilot study will test the hypothesis that prolonged regional peripheral nerve block will reduce development of chronic pain in patients undergoing surgery for ankle fracture. Regional nerve block using local anesthetics delivered by ambulatory pump is used in some types of surgeries but is not routine for ankle fracture ...


Effectiveness of DentalVibe in Reducing Injection Pain and Anxiety During Local Anaesthesia in Children

Achieving local anaesthesia in children is one of the critical aspects of pain management. In recent years, several innovative dental appliances have been developed on the concept to reduce the pain of needle injection by applying pressure, vibration, microoscillations or a combination of them. he aim of this study is ...

Phase N/A

Ultrasound-guided Peripheral Nerve Block Versus Forearm Bier's Block in Patients Undergoing Carpal Tunnel Release

Introduction In Belgium, several ways of anesthesia are used to perform hand surgery, being general anesthesia, intravenous regional anesthesia as well as locoregional anesthesia. Locoregional anesthesia and intravenous regional anesthesia are often performed since patients can be discharged from the hospital more rapidly. A forearm intravenous regional anesthesia (IVRA; mini-Bier's ...

Phase N/A

Patients are needed to participate in a clinical research study of Ultrasound, Spinal Anesthesia, ultrasonic diagnosis, Scoliosis to evaluate 0.5% heavy bupivacaine

Spinal anesthesia can be challenging in patients with lumbar scoliosis or previous lumbar spine surgery. This study aims to evaluate whether the use of the ultrasound-assisted spinal anesthesia reduces the number of passes required to successful dural puncture compared with the conventional surface landmark-guided technique in patients with abnormal spinal ...

Phase N/A

Patients are needed to participate in a clinical research study for the treatment of Opioid Use, Local anesthesia, Malignant neoplasm of prostate, bladder cancer, Pelvic Neoplasm, Postoperative pain, urinary tract neoplasm

Purpose: To improve analgesia and reduce opioid consumption in patients undergoing major urologic surgery. Hypothesis: Patients receiving pre-operative single shot rectus sheath blockade in addition to continuous rectus sheath catheters will use less PCA opioid in the first 24 hours post-operatively compared to patients receiving continuous rectus sheath blockade for ...

Phase N/A