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Anesthesia (Local) Clinical Trials

A listing of Anesthesia (Local) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (103) clinical trials

Serratus Intercostal Plane Block in Video Assisted Thoracic Surgery

The proposed randomized controlled trial aims at comparing the opioid use per- and postoperatively in patients with versus without SIP block undergoing VATS. We hypothesize that use of a SIP block results in less opioid use during and the first 24 hours after VATS as compared with patients without SIP ...

Phase N/A

PACMAN Ultrasound Recording Data Collection

Study to collect videos of ultrasound recordings during peripheral nerve block procedures.

Phase N/A

Interaction of Sevoflurane Propofol and Remifentanil in Anesthesia for Laparoscopic Surgery

Background In general anesthesia propofol or volatile anesthetic are usually combined with opioids and the synergy between hypnotics and opioids is used to reduce the dose of each component in order to minimize side effects and to allow a rapid recovery. Current pharmacodynamic interaction models allow to estimate the potency ...


A Study in Healthy Male Volunteers to Investigate the Safety and Tolerability of a Single Dose of Neosaxitoxin Alone and in Combination With Bupivacaine (With and Without Epinephrine) for Brachial Plexus Blockade

Neosaxitoxin is a new compound that is in clinical development as local anesthetic for surgical anesthesia and postoperative analgesia. The primary objective of this study is to evaluate the systemic and local safety and tolerability of ascending doses of neosaxitoxin alone and in combination with fixed doses of bupivacaine (with ...


Variable Perception of Cutaneous Stimulation

Perception of cutaneous sensory stimulation shows a large range of variability across multiple populations. Understanding this variability is critical to medical practice as interpretation of discomfort and pain is critical to diagnosis and treatment. Further, procedural medicine involves inflicting pain on patients in the form of injection of local anesthetic. ...

Phase N/A

Combined Spinal-epidural Anesthesia for Cesarean Section Without Prophylactical Prehydration and Vasopressors

General: This was a single-centre randomized controlled trial performed at ShenZhen People's Hospital of Jinan University. Study protocol was approval was by the Ethics Committee of ShenZhen People's Hospital of Jinan University, ShenZhen, China (Permit No. SZY-00251, Chairperson Prof. Xiaofang Yu) on 8 February 2017. Pregnant women who were scheduled ...

Phase N/A

Preventive Intramuscular Phenylephrine in Elective Cesarean Section Under Spinal Anesthesia

Hypotension often occurred in parturients undergoing cesarean section in spinal anesthesia. This study aims to determine whether preventive intramuscular phenylephrine can better the fetal acid-base state and maternal hemodynamics.

Phase N/A

The Effect of Local Anesthesia on Postoperative Pain in Vaginal Hysterectomy

This is a randomized, controlled trial. To indicate a clinically significant reduction of postoperative pain, a sample size of 50 patients was calculated. Women admitted for elective vaginal hysterectomy, with or without anterior/posterior colporaphy, on benign indication would be offered to participate in the study. Exclusion criteria include age<18 years, ...

Phase N/A

Influence of Injection Rate of Intrathecal Mixture of Local Anesthesia on Hypotension in Cesarean Section

Patients admitted to undergo elective c-section under spinal anesthesia will be randomized using the sealed envelope technique to Group I who will receive intrathecal injection in a slow speed 1ml in 15 sec and group II who will receive 1ml in 5 sec. The baseline pulse rate, blood pressure, respiratory ...

Phase N/A

Femoral Triangle Block: Early Mobilization and Postoperative Analgesia After Total Knee Arthroplasty

The objective of this trial is to compare the efficacy of three different nerve blocks as an analgesic option after total knee arthroplasty (TKA), based on muscle strength, mobilization and pain. The Adductor Canal Block has been proposed as an equally effective technique to the Femoral Nerve Block in terms ...

Phase N/A