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Cystic Fibrosis Clinical Trials

A listing of Cystic Fibrosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (205) clinical trials

Perceived Impact of Art Therapy in Patients With Cystic Fibrosis and in Professional Interdisciplinary Teams Taking Care of Them.

Cystic fibrosis is so far a disease whose treatment remains essentially symptomatic care teams perceive the boundaries of a support mainly focused on drug treatments. The patient had no other choice but to learn to live with their disease, the goal is to make every effort so that tames the ...

Phase N/A

Cystic Fibrosis - Insulin Deficiency Early Action

As well as progressive lung disease, patients with Cystic Fibrosis (CF) suffer pancreatic destruction, leading to slow but progressive insulin deficiency. Deficiency of insulin, a powerful anabolic hormone, causes accelerated decline of weight and lung function (important predictors of early mortality in CF). We analysed Oral Glucose Tolerance Tests sampled ...


Portal Hypertension and Systemic Endothelial Function

Prospective , monocentric study, with four groups of patients: Patients with cystic fibrosis and PHT Cystic fibrosis patients without PHT Patients free from cystic fibrosis with PHT from other causes Healthy controls. One study visit, no follow-up. During the visit the following examinations will be performed: Collection of a blood ...

Phase N/A

A Study to Evaluate the Safety Pharmacokinetics and Pharmacodynamics of Ivacaftor in Subjects With Cystic Fibrosis Who Are Less Than 24 Months of Age and Have a CFTR Gating Mutation

The purpose of this study is to evaluate the safety of ivacaftor treatment, and PK of ivacaftor and metabolites in subjects with cystic fibrosis (CF) who are <24 months of age at treatment initiation and have a CF transmembrane conductance regulator (CFTR) gene gating mutation


Clinical Effects of Exercise Program Added to Pulmonary Rehabilitation in Patients With Cystic Fibrosis

Cystic fibrosis (CF) is an autosomal recessive, multisystem involvement disease. The most important cause of mortality in CF is pulmonary complications. Prevention of pulmonary complications is only possible with pulmonary rehabilitation. Pulmonary rehabilitation methods used in CF are called airway cleaning techniques that include postural drainage, breathing techniques and use ...

Phase N/A

Longitudinal Pathogen-colonization in Cystic Fibrosis Airways and Ability to Smell

The sub-study on the sense of smelling in CF has been finalized in the meantime. Results were published in 2012: Smell in cystic fibrosis. Lindig J, Steger C, Beiersdorf N, Michl R, Beck JF, Hummel T, Mainz JG. Eur Arch Otorhinolaryngol. 2013 Mar;270(3):915-21. doi: 10.1007/s00405-012-2124-2. Epub 2012 Aug 14.

Phase N/A

Program Of Exercises During The Hospitalization Of Children And Adolescents With Cystic Fibrosis

The objective of the study is to evaluate the effect of a protocol of physical exercises on the functional capacity of children and adolescents with cystic fibrosis, hospitalized, in the stage of exacerbation of the disease. In the first 48 hours of hospitalization patients and their caregivers will be invited ...

Phase N/A

Surrogate Markers of Response to New Therapies in Cystic Fibrosis Patients

This study is based upon the hypothesis that clinical response of cystic fibrosis patients to CFTR modulators is correlated to in vitro responses to these drugs of epithelial cells derived from the patients, as assessed by CFTR-dependent Chloride secretion. Epithelial cells will be derived either from nasal or rectal epithelia, ...

Phase N/A

Impaired Secretory IgA and Mucosal Immunity in Cystic Fibrosis

Impaired secretory IgA and mucosal immunity in cystic fibrosis: role of CFTR-related epithelial changes in the regulation of pIgR-mediated IgA transcytosis and contribution to lung pathology and impaired defence against bacterial infections. PROJECT DESCRIPTION Cystic fibrosis (CF) represents the most common lethal autosomal recessive disorder in the white population, mainly ...

Phase N/A