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Essential Tremor Clinical Trials

A listing of Essential Tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (11) clinical trials

Biomarkers in Neural Disorders

Parkinson's disease (PD), a devastating age-related disease that is clinically defined by its effects on the motor system, afflicts more than six million people worldwide, imposing enormous burdens on patients, relatives, caretakers, and society in general. Diagnostic errors are common, particularly as symptoms first arise. The most common misdiagnoses are ...

Phase N/A

Stereotactic Radiosurgery for Essential Tremor and Parkinsonian Tremor

Tremor is the most common of all movement disorders. Patients with essential tremor (ET) or Parkinsonian tremor (PT) may be severely disabled by their tremor. When the tremor is inadequately controlled by medications, surgical options are often offered. However, some patients may prefer a noninvasive treatment approach and some patients ...

Phase N/A

Voice and Swallowing Outcomes Following Revision Anterior Cervical Spine Surgery

Anterior Cervical Decompression and fusion is one of the most common spinal surgical procedures performed in the United States. Common complications of this type of surgery are difficulty swallowing and nerve dysfunction that can effect voice. The chance of having voice and swallowing disturbances increases if this type of surgery ...

Phase N/A

Defining Phenotypes of Movement Disorders :Parkinson's Plus Disorders (PD) Essential Tremor (ET) Cortical Basal Degeneration (CBD) Multiple Systems Atrophy (MSA) Magnetoencephalography.

Specific Aim 1: Determine which features of resting Magnetoencephalography (MEG) brain activity most sensitively discriminate between PD with normal cognition, PD with mild cognitive impairment (MCI), and PD dementia (PDD). Investigators predict that frontal network slowing and connectivity will discriminate between normal cognition and MCI while visuospatial network involvement will ...

Phase N/A

Physiological Brain Atlas Development

Purpose To create a brain atlas that will allow physiological and clinical information to be assigned to anatomical locations in MRI space, utilizing non-rigid MRI normalization algorithms. These data will specifically be acquired from the population of patients undergoing stereotactic brain procedures. 2. To collate and analyze the brain data ...

Phase N/A

Global Registry: ExAblate Neuro MR Guided Focused Ultrasound (MRgFUS) of Neurological Disorders:

A global, multi-center, open-label, observational registry to capture safety and effectiveness data related to ExAblate Neuro, an MRI guided focused ultrasound device designed to lesion tissue deep within the brain using sound waves without the need for craniotomy. This registry includes certain regional and country specific approved thalamotomy and pallidotomy ...

Phase N/A

Imaging Genetics of Spasmodic Dysphonia

Spasmodic dysphonia (SD) is an isolated focal laryngeal dystonia characterized by selective impairment of voluntary voice control during speech production. Despite well-characterized clinical features of SD, its causes and pathophysiology remain unclear. Consequently, the absence of objective biomarkers of SD leads to diagnostic inaccuracies, while the lack of understanding of ...

Phase N/A

Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor

Objectives To explore a neurophysiological difference between patients with essential tremor (ET) and dystonic tremor (DT). Sample Size and Population: We plan to recruit 26 healthy volunteers (HVs), 26 patients with ET, 26 patients with dystonic tremor from the Movement Disorders and Botulinum Toxin (BoNT) clinics of HMCS. The dystonic ...

Phase N/A

Clinical and Physiological Studies of Tremor Syndromes

Objectives The purpose of this protocol is to study the phenotypic spectrum and the pathophysiology of tremor syndromes by performing small behavioral, electrophysiological and neuroimaging sub-studies. The protocol includes techniques with minimal risk (standard clinical evaluation, MRI, EEG, peripheral nerve stimulation, single and paired pulse TMS) and certain sub-studies may ...

Phase N/A

The Motor Network in Essential Tremor: Mechanisms of Therapy

The research study goal is to advance the understanding of the mechanisms for essential tremor through brain recordings. The investigators will collect brain signals in persons with essential tremor undergoing neurosurgical treatment (deep brain stimulation implantation). By recording from the implanted electrodes for deep brain stimulation along with two other ...

Phase N/A