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Essential Tremor Clinical Trials

A listing of Essential Tremor medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (25) clinical trials

Learn about a new clinical trial for essential tremor (ET) The T-CALM study will evaluate whether investigational oral drug CX-8998 reduces the severity of tremors by reducing abnormal activity in certain regions of the brain. Eligibility Criteria: Eligibility requirements include: - Men and women (not pregnant or breastfeeding) 18 to ...

Phase N/A

Deep braIn Stimulation for Tremor TractographIC Versus Traditional

In this monocentric, randomized, controlled, 2 arms, interventional, observer-blinded feasibility trial patients suffering from therapy resistant essential tremor (ET) will be treated with Deep Brain Stimulation (DBS). After screening (e.g. obtaining informed consent, assessment of inclusion/exclusion criteria etc.) patients will be randomized to one of the following groups: Group 1 ...

Phase N/A

ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders

The purpose of this study is to evaluate the safety and initial effectiveness of MRI-guided focused ultrasound thermal ablation of a designated area in the brain of patients suffering from movement disorder symptoms: FUS under MRI-guidance and MRI-based thermometry can be safely delivered to patients suffering from treatment-refractory movement disorders ...

Phase N/A

Responsive Deep Brain Stimulator for Essential Tremor

The purpose of this study is to investigate brain signals related to intention tremor in essential tremor in order to deliver deep brain stimulation only when the patient is showing symptoms. By delivering stimulation only when needed, the investigators hypothesize that the treatment will be more effective, will cause fewer ...

Phase N/A

Botulinum Toxin Type A for Injection of Bilateral Upper Extremity Tremor in Patients With Essential Tremor Using Kinematic Assessment

The primary objective is to study the efficacy of botulinum toxin type A (Xeomin) injected utilizing kinematically-based injection parameters for the treatment of upper extremity essential tremor (ET). Additional objectives are to study the benefit of kinematic assessment tools in determining injection parameters and to study the composition of tremor ...

Phase

Evaluation of Botulinum Toxin Injection Efficacy in the Treatment of Head Essential Tremor

Type of study: multi-center, randomized, double-blind, parallel-group, placebo-controlled therapeutic clinical trial. Number of centers: 13 centers : Clermont-Ferrand, Paris (Fondation Rothschild et APHP), Toulouse, Lyon, Amiens, Bordeaux, Narbonne, Lille, Strasbourg, Nmes, Marseille, Besanon. Medical product Botulinum toxin type A, 200U (BOTOX 200 Units, Allergan) Patients Patients eligible for inclusion will ...

Phase

Sodium Oxybate in Spasmodic Dysphonia and Voice Tremor

Spasmodic dysphonia (SD), or laryngeal dystonia, is a chronic debilitating condition that selectively affects speech production due to involuntary spasms in the laryngeal muscles. SD often extends beyond the impairment of vocal communication causing significant occupational disability and life-long social isolation. SD becomes even more incapacitating when it is associated ...

Phase

RAD 1601: EDGE Radiosurgery for Intractable Essential Tremor and Tremor-Dominant Parkinson's Disease

Per the National Institute of Neurological Disorders and Stroke, tremor is an involuntary, rhythmic muscle contraction leading to shaking movements in one or more parts of the body. It is a common movement disorder that most often affects the upper extremities but can also occur in the head, vocal cords, ...

Phase N/A

Investigation of the Role of Steroids in Enhancing Voice Therapy Outcomes

The study will investigate the potential added advantage of the use of steroids in patients undergoing voice therapy. Enrolled subjects will be randomized using a random numbers table to either receive oral steroids or no steroids prior to the initiation of voice therapy. The therapist and individuals involved in the ...

Phase N/A

A Phase 2 RCT Study of CX-8998 for Essential Tremor

This is a multicenter, double-blind, placebo-controlled, parallel-group study consisting of a screening period of up to 4 weeks (with the exception of subjects on primidone at baseline who will be allowed 6 weeks of screening to allow for safe discontinuation). Screening results from all patients meeting the eligibility requirements will ...

Phase