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Lung Injury Clinical Trials

A listing of Lung Injury medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (29) clinical trials

Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys

The overarching purpose of SATISFY-SOS is to implement a rigorous process to assess short-term and intermediate-term outcomes of surgical and procedural patients who receive anesthesia services at Barnes-Jewish Hospital facilities, located in St. Louis, Missouri. Specifically, patients will be followed for major morbidity events, for mortality, and for quality of ...

Phase N/A

Measurement of Lung Elastance and Transpulmonary Pressure Using Two Different Methods (Lungbarometry)

Classically lung elastance and transpulmonary pressure are measured from the difference in tidal variations of airway pressure subtracted by tidal variations in esophageal pressure divided by the tidal volume (Method 1). This requires the presence of a esophageal balloon catheter which is cumbersome and costly. In this study values obtained ...

Phase N/A

A New Ultrasonographic Tool to Assess Pulmonary Strain in the ICU

Mechanical ventilation is frequently used in the intensive care settings. Although essential in many cases, mechanical ventilation can be responsible for ventilator-induced lung injury (VILI). The relationship between mechanical ventilation and VILI has been clearly demonstrated in animals and is highly suspected in humans. The putative mechanism responsible for VILI ...

Phase N/A

Cardiovascular Biomarkers and Lung Edema in Severe Burns Patients

Burn injury leads to hypovolemic then distributive shock. Fluid resuscitation remains the cornerstone of initial treatment of burn shock. However, fluid rescucitation can lead to fluid overload, which manifests most notably as lung edema. The peptide NT-pro-BNP, a biomarker of cardiac congestion secreted by the myocardium, as well as plasma ...

Phase N/A

Early Detection and Staging of Endobronchial Lung and Pleural Cancer Airway Injury and Prostate Cancer

Optical coherence tomography is a non-invasive diagnostic technique that can provide information about tissue abnormalities, change in structure of an organ. This technique uses a near-infrared diode to emit light that can produce images of the specimen under investigation without causing damage or alterations.

Phase N/A

Acute Kidney Injury in Children After Cardiopulmonary Bypass

Acute kidney injury (AKI) is a common complication in patients with congenital heart defects after cardiopulmonary bypass (DentC.L.,MaQ., 2007, PedersenK.R., HjortdalV.E., 2008, Zappitelli M., BernierP .L., 2009). The death rate from AKI in critically ill children remains high and reaches 60% (FlynnJ.T., 2002). The basic criteria for diagnosing and assessing ...

Phase N/A

Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery

There have been a number of studies that have examined a link between intraoperative decreases in rSO2 and adverse perioperative outcome3-7. These studies, the vast majority of which have been in the setting of cardiac surgery, suggest that decreases in rSO2 (as detected by near-infrared spectroscopy) may be related to ...

Phase N/A

Measuring Energy Expenditure in ECMO (Extracorporeal Membrane Oxygenation) Patients

With the perception that lung protective ventilation with regard to low tidal volume ventilation and limiting airway pressures improves outcome in ARDS (acute respiratory distress syndrome) and that the development of new technical devices of extracorporeal lung assist systems with lower complication rates support establishment of lung protective ventilation strategies ...

Phase N/A

Viral Illness in Pediatric Critical Care: Incidence Timing & Severity of Associated Heart Dysfunction & Acute Kidney Injury

This is a single-centre, prospective and retrospective, descriptive data-collection pilot study. Prospective Data Collection: All pediatric patients who are less than 18 years with a confirmed positive respiratory viral swab will be invited to participate. Retrospective Data Collection: The retrospective portion of this study will examine a 5 year period ...

Phase N/A

Effectiveness of NephroCheckTM Test to Predict Acute Kidney Injury Following Advanced Cardiac Replacement Therapies

Current strategies for AKI detection rely primarily on elevations in serum creatinine in conjunction with diminished urine output. Unfortunately, deviations in these crude parameters of renal function are largely insensitive and late manifestations of AKI, where acute tubular necrosis has likely already transpired and therefore well beyond the phase where ...

Phase N/A