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Nasal Obstruction Clinical Trials

A listing of Nasal Obstruction medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (9) clinical trials

Effect of Mepolizumab (currently an approved medication for patients with asthma), or placebo for patients with severe nasal polyps This research study may be an option for you. Please see the eligibility criteria to see if you may qualify. Please reach out to our research staff if you have any ...


Dr. Craig LaForce, Dr. Karen Dunn and Dr. Magda Pugh are recruiting individuals with nasal polyps to participate in a research study involving an investigational medication

Phase N/A

Efficacy and Physiology of Nasal High Flow Therapy

Stage 1: Respiratory Physiology. Aim of this Stage is to investigate the effects of nasal High Flow (NHF) therapy in patients in progressed stages of COPD, by measuring physiologic parameters like tidal volume, breathing frequency and expiratory PCO2 concentration. Stage 2: Efficacy of short term NHF. Aim of this Stage ...

Phase N/A

Spirox Latera Implant Support of Lateral Nasal Wall Cartilage (LATERAL-OFFICE) Study

To obtain outcomes data in subjects with severe to extreme class NOSE scores undergoing placement of the Spirox Latera Implant with or without concurrent turbinate reduction procedures in an office setting.

Phase N/A

Nasal High Flow Therapy 30 Day Readmission Study

The aim of this feasibility study is to provide data for a subsequent randomized controlled trial to investigate if patient outcomes will be improved after an acute COPD exacerbation using domiciliary nasal high flow therapy (NHF) compared to standard care. This feasibility study will investigate the following: process, resources, management ...

Phase N/A

Pilot Study of Physiological Effect of High-Flow Nasal Cannula on Respiratory Pattern and Work of Breathing

HFNC has been shown to have many advantages in the treatment of acutely hypoxemic patients, improving their clinical outcome. The exact mechanism underlying this beneficial effect is still not completely understood. Few studies have analyzed the effect of HFNC on ventilatory pattern and work of breathing. The majority of these ...

Phase N/A

Treatment Outcome Using Vivaer Stylus to Treat Nasal Airway Obstruction

This is a non-significant risk, prospective, non-randomized study to evaluate subjective and objective measures of nasal obstruction both before and after treatment with the Vivaer Stylus. The Stylus is used to deliver radiofrequency (RF) energy to the nasal valve area to improve symptoms in those diagnosed with nasal airway obstruction.

Phase N/A

Effects of Nasal High-flow Oxygen in Patients With an Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

Patients admitted to the hospital with an exacerbation of COPD accompanied by respiratory failure need supplemental oxygen and alleviation of an increased work of breathing. Patients with acute exacerbations of COPD have hypoxemia, hypercapnia and an elevated work of breathing due to increased airways obstruction and hyperinflation. Patient outcomes can ...

Phase N/A

Sleep and Daytime Use of Humidified Nasal High-flow Oxygen in COPD Outpatients

Humidified Nasal High-flow with Oxygen (HNHF-O2) therapy has been reported to have acute beneficial effects in patients with hypoxemic respiratory failure. HNHF-O2 may be beneficial in patients with COPD and chronic impairments in gas exchange, both hypoxemia as well as hypercapnia. HNHF-O2 may decrease work of breathing, reduce dyspnea, improve ...

Phase N/A