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Crohn's Disease Clinical Trials

A listing of Crohn's Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (282) clinical trials

Crohn’s Disease – Moderate to Severe

Phase N/A

The purpose of the study is to look at the effect of small bowel Crohn's disease on lipoprotein after ingestion of a fatty meal in participants with and without Crohn's disease.

Phase N/A

A research study is evaluating an investigational medication for moderate to severe Crohn’s disease for people who have an inadequate response or intolerant to conventional therapies.

Phase N/A

Calcium Supplements Strategy for Kidney Stones Prevention in Crohn's Patients

The primary objective of this study is to establish optimal oral calcium supplementation in Crohn's patients who have had an ileal bowel resection. This population is at high risk for calcium oxalate kidney stones, a direct consequence of extensive gut malabsorption and enteric hyperoxaluria. The benefit of providing oral calcium ...

Phase N/A

Observational Study Evaluating the Effectiveness of Drug Concentration to Predict the Recapture of Response in Crohn's Disease Patients With Loss of Response ( PRADA )

This is a multi-center study that explores the relationship between recapture of response with escalation to weekly adalimumab and trough adalimumab concentration before escalation in patients experiencing lack of response (LOR).

Phase N/A

A Study to Assess the Effectiveness and Safety of Treatment With Vedolizumab in Adult Participants With Ulcerative Colitis (UC) or Crohn's Disease (CD) in Real Life

This is a prospective, non-interventional and pharmaco-epidemiological study of participants with IBD. The study will provide the real-life data of treatment effectiveness and safety of vedolizumab in adult participants with UC or CD. The study will enroll approximately 300 participants. All participants will be enrolled in one observational group: Vedolizumab ...

Phase N/A

MRI Differentiating Gut TB and Crohn's

The clinical presentation of gut tuberculosis and Crohn's disease is very similar. In areas endemic of tuberculosis infection, differentiating the two diseases remains difficult. Both disease entities can have similar clinical, endoscopic and histological findings. Yet, wrongly diagnosing gut tuberculosis as Crohn's disease can potentially result in disastrous outcomes, especially ...

Phase N/A

Reverse Engineering of Exclusive Enteral Nutrition

This will be an open label, pilot study over 8 weeks in children with newly diagnosed Crohn's disease treated with a smoothie designed to emulate formulas used for exclusive enteral nutritional therapy. In place of formula, whole-foods based smoothie recipes and the food to create the smoothies will be given ...

Phase N/A

Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery

The primary objectives of this study are to evaluate the potential for preoperative pharmacogenomics (PGx) testing to positively influence postoperative opioid use through visual analog scale (VAS) guided administration of narcotic equivalent and lower pain scores as measured by OBAS in patients undergoing major abdominal surgery.

Phase N/A

Addressing Depression and Anxiety Symptoms in Patients With Inflammatory Bowel Disease

Inflammatory Bowel Diseases (IBD) are chronic debilitating disorders of the gastrointestinal tract that comprise two subtypes; Crohn's Disease (CD) and Ulcerative Colitis (UC). Canada has among the highest incidence rates of CD and UC in the world, as high as 20.2 and 19.5 per 100,000 respectively. Although, IBD can occur ...

Phase N/A