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Leukemia (Pediatric) Clinical Trials

A listing of Leukemia (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (12) clinical trials

A Phase 1 clinical study for patients with childhood ALL, Acute myeloid leukemia, Preleukemia, Chronic myeloid leukemia, MYELODYSPLASTIC SYNDROME

This will be a Phase 1, open-label study of DS-3032b to assess its safety and tolerability and identify a Maximum Tolerated Dose (MTD)/tentative Recommended Phase II Dose (RP2D) in subjects with refractory or relapsed Acute Myelogenous Leukemia (AML), Acute Lymphocytic Leukemia (ALL), Chronic Myelogenous Leukemia (CML) in blast phase, or ...


A clinical trial to evaluate treatments using Chemotherapy, Navitoclax, Venetoclax for patients with childhood ALL

This dose-escalating study is to determine the safety, pharmacokinetics, and preliminary efficacy of venetoclax in combination with navitoclax and chemotherapy in adult and pediatric participants with relapsed acute lymphoblastic leukemia.


Patients are needed to participate in a clinical research study for the treatment of childhood ALL, Lymphoma, leukemia

The GMALL registry serves the purpose of ALL research and quality assurance. The Registry collects data about diagnostics, treatment and outcome of Adult ALL Patients in the clinical routine, whether or not the patient is treated within a clinical trial.

Phase N/A

A clinical trial to evaluate treatments for patients with childhood ALL, Obesity, Pediatric

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy with survival exceeding 90%. However, treatment-related toxicity remains a clinical challenge during and after treatment. Evidence-based, nutritional interventions may minimize the development of nutrition-related toxicities, such as bone morbidities, hypertriglyceridemia, and obesity. To date, no effective interventions are available to ...

Phase N/A

A clinical trial to evaluate treatments using Dasatinib, Methotrexate, Vincristine Sulfate, Prednisone, Mercaptopurine for patients

PRIMARY OBJECTIVES: I. To evaluate the 3-year survival rate in elderly patients with newly diagnosed Philadelphia (Ph)-negative acute lymphoblastic leukemia (ALL) treated with blinatumomab followed by POMP (prednisone, vincristine sulfate, methotrexate, and mercaptopurine) maintenance. II. To evaluate in a preliminary manner (feasibility study) the safety of dasatinib-steroid based induction followed ...


A clinical research study of Mercaptopurine, Daunorubicin Hydrochloride, Prednisone, Cytarabine, Cyclophosphamide, Pegaspargase, Etoposide, Vincristine Sulfate, Methotrexate, Dexamethasone for the treatment of childhood ALL, B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative, BCR/ABL1 Fusion Protein Negative, Untreated Adult Acute Lymphoblastic Leukemia

PRIMARY OBJECTIVES: I. To compare the overall survival (OS) of blinatumomab in conjunction with chemotherapy to chemotherapy alone in patients with BCR-ABL-negative B cell precursor acute lymphoblastic leukemia (ALL) who are minimal residual disease (MRD) positive after induction and intensification chemotherapy, based on multiparameter flow cytometric (MFC) assessment of residual ...


Patients are needed to participate in a clinical research study of Anti-thymocyte globulin, Bone marrow transplant from a related donor, Tacrolimus

The induction of transplantation tolerance involves the specific elimination of the immune response to the transplant but not to other antigens. In the realm of kidney transplantation, tolerance means that the recipient is unable to detect the donor transplant kidney as foreign, and therefore the recipient is unable to reject ...

Phase N/A

A Phase 3 clinical study for patients using Mycophenolate mofetil, methotrexate, Methotrexate (low dose), tacrolimus

Study Design This is a prospective randomized trial to determine the effectiveness of different doses of GVHD prophylaxis on mucositis, engraftment and aGVHD. Study consists of two study groups of 50 subjects each. Group A will receive Tac and MTX (15 mg/m2 day +1, 10 mg/m2 day +3, +6, +11). ...


A clinical trial sponsored by University of Arizona for a research study for the treatment of Juvenile Myelomonocytic Leukemia, MALT Lymphoma, Diffuse Large B-Cell Lymphoma, Acute myeloid leukemia, Burkitt's Lymphoma, Hodgkin's Disease, MYELODYSPLASTIC SYNDROME, Gray Zone Lymphoma, childhood ALL, follicular lymphoma, Chronic myeloid leukemia, Lymphoma, Preleukemia, Mantle cell lymphoma

This study will follow the standard-of-care bone marrow transplant (BMT), with the only exception being to gradually substitute post-transplant cyclophosphamide (on day +4 after BMT) with bendamustine. Three dose levels are planned for the phase I component of the study, consisting of a combination of sequentially reduced doses of cyclophosphamide ...