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Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (37) clinical trials

Studying Patients With a Personal or Family History of Cancer Caused by a Virus

OBJECTIVES: - Conduct clinical, laboratory, and epidemiologic studies of patients with a personal or family history of viral-associated cancer. OUTLINE: Patients undergo an interview, physical examination, and blood sample collection. Other clinically indicated biological samples, such as urine, sputum, saliva, tears, or semen or cervical, anal, oral, or nasal swabs, ...

Phase N/A

Fibrosis a New Pathological Actor in Adipose Tissue

Adipose tissue (AT) has specific alterations in obesity that could link obesity to its comorbidities. In particular increased fibrosis abundance in AT has been observed in obese compared to lean subjects. The investigators previously observed that the amount of fibrosis in AT measured at baseline could predict surgery-induced weight loss. ...

Phase N/A

Employment and Arthritis: Making it Work

The investigators plan to conduct a randomized controlled trial to evaluate the effectiveness and the cost effectiveness of an on-line eLearning program (entitled Employment and Arthritis: Making it Work) designed to help people with inflammatory arthritis stay employed. The program also includes assessments with 1) an occupational therapist, and 2) ...

Phase N/A

Pediatric MATCH: Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors Non-Hodgkin Lymphoma or Histiocytic Disorders With BRAF V600 Mutations

PRIMARY OBJECTIVES: I. To determine the objective response rate (ORR; complete response + partial response) in pediatric patients treated with vemurafenib with advanced solid tumors (including central nervous system [CNS] tumors), lymphomas or histiocytic disorders that harbor activating BRAF V600 mutations. SECONDARY OBJECTIVES: I. To estimate the progression free survival ...

Phase

A Randomized Trial of The Effectiveness of Aromatherapy on Chemotherapy Induced Nausea and Vomiting in Children With Cancer

Nausea and vomiting remain two of the most distressing symptoms to children being treated for cancer. Nausea and vomiting are directly associated with the administration of chemotherapy, due to effects of the chemotherapy on the gastrointestinal mucosa, and certain chemotherapeutic agents, such as cisplatin, are known to be particularly emetogenic. ...

Phase N/A

Urotensin II and Vascular Tone in Cirrhosis

This study looks at the iontophoresis of urotensin II in chronic liver disease patients.

Phase N/A

Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors

Significant advances have been made in recent years in the treatment of solid tumors of childhood. However, much of the improvement in survival has been made in low stage and localized disease. Of significance is the fact that the improvements have come in up-front remission rates without translation into significantly ...

Phase

A Study to Evaluate the Efficacy and Safety of CC-90001 in Subjects With Idiopathic Pulmonary Fibrosis

Approximately 135 adult male and female subjects with a confirmed diagnosis of Idiopathic pulmonary fibrosis (IPF) (according to the most recent IPF guideline for diagnosis and management) will be randomized 1:1:1 (45 subjects per arm) to treatment with oral CC-90001 (200 mg QD or 400 mg QD) or matching placebo ...

Phase

Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers

This protocol describes a prospective screening study at Odense University Hospital, Department of Gastroenterology and Hepatology. The investigators will use liver stiffness measurements with transient elastography to screen 3000 patients from at-risk populations and 1000 participants from the general population for advanced liver fibrosis. At-risk is defined as either (A) ...

Phase N/A

HMB for Denutrition in Patients With Cirrhosis (HEPATIC)

Scientific & technical aspects State of the art: Patients with cirrhosis present a chronic inflammatory state and alterations in protein metabolism. These alterations lead to elevated levels of insulin and catecholamines along with the development of glucose intolerance and insulin resistance. The reduced availability of glucose as energy source translates ...

Phase N/A