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Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (20) clinical trials

A Protocol of the Canadian Prospective Study for Hepatocellular Carcinoma Surveillance Using Biomarkers

This study is a prospective randomized controlled trial (RCT) comparing surveillance for hepatocellular carcinoma with ultrasound alone versus ultrasound and standard biomarkers. The study will be conducted initially at UHN (TGH and TWH). One arm will undergo surveillance for hepatocellular carcinoma using ultrasound (US) alone and the other will undergo ...

Phase N/A

Incisional Negative Pressure Wound Therapy for Preoperatively Irradiated Lower Extremity Soft Tissue Sarcoma Wounds

Postoperative surgical site infections pose a significant challenge to the orthopaedic oncologist, especially in wounds that have been previously irradiated with neo adjuvant external beam radiation therapy (EBRT). There are many studies demonstrating the relatively high risk of wound complications after lower extremity sarcoma resection. Published data suggest that these ...

Phase N/A

Determination of Kidney Function

The study of various kidney disorders will be facilitated by determinations of true glomerular filtration rate and/or effective renal plasma flow employing inulin or non-radioactive iothalamate and/or para aminohippurate (PAH), respectively. Selected patients with proteinuria will be asked to participate in studies of glomerular capillary wall permselectivity calculated from the ...

Phase N/A

Evaluation and Treatment of Patients With Connective Tissue Disease

This protocol allows for the screening and diagnosis of a broad array of patients with disorders of bone and connective tissue, and in so doing to expand our knowledge about these disorders and provide access to patients of interest for research, teaching, and clinical experience. This protocol also serves as ...

Phase N/A

Studying Patients With a Personal or Family History of Cancer Caused by a Virus

OBJECTIVES: - Conduct clinical, laboratory, and epidemiologic studies of patients with a personal or family history of viral-associated cancer. OUTLINE: Patients undergo an interview, physical examination, and blood sample collection. Other clinically indicated biological samples, such as urine, sputum, saliva, tears, or semen or cervical, anal, oral, or nasal swabs, ...

Phase N/A

HMB for Denutrition in Patients With Cirrhosis (HEPATIC)

Scientific & technical aspects State of the art: Patients with cirrhosis present a chronic inflammatory state and alterations in protein metabolism. These alterations lead to elevated levels of insulin and catecholamines along with the development of glucose intolerance and insulin resistance. The reduced availability of glucose as energy source translates ...

Phase N/A

A Randomized Trial of The Effectiveness of Aromatherapy on Chemotherapy Induced Nausea and Vomiting in Children With Cancer

Nausea and vomiting remain two of the most distressing symptoms to children being treated for cancer. Nausea and vomiting are directly associated with the administration of chemotherapy, due to effects of the chemotherapy on the gastrointestinal mucosa, and certain chemotherapeutic agents, such as cisplatin, are known to be particularly emetogenic. ...

Phase N/A

Urotensin II and Vascular Tone in Cirrhosis

This study looks at the iontophoresis of urotensin II in chronic liver disease patients.

Phase N/A

Screening At-risk Populations for Hepatic Fibrosis With Non-invasive Markers

This protocol describes a prospective screening study at Odense University Hospital, Department of Gastroenterology and Hepatology. The investigators will use liver stiffness measurements with transient elastography to screen 3000 patients from at-risk populations and 1000 participants from the general population for advanced liver fibrosis. At-risk is defined as either (A) ...

Phase N/A

Identification of New Biomarkers to Promote Personalized Treatment of Patients With Inflammatory Rheumatic Diseases

Introduction: The medical treatment of inflammatory rheumatic diseases has improved dramatically during the last decades primarily due to the introduction of biological disease modifying anti-rheumatic drugs (bDMARDs). However, bDMARD treatment failure occurs in 30-40% of patients due to lack of effectiveness or side effects. The tools to predict treatment outcomes ...

Phase N/A