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Congenital Heart Disease Clinical Trials

A listing of Congenital Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (39) clinical trials

Molecular Basis of Congenital Heart Defects

Purpose: The purpose of this study is to evaluate the role of mutation of genes in congenital heart diseases and study the genotype-phenotype correlation. Hypothesis: The central hypothesis is that a significant percentage of congenital heart disease is caused by mutation of genes involved in heart development, and the phenotype ...

Phase N/A

Molecular Determinants of Coronaruy Artery Disease

The purpose of this study is to discover genes that may cause Coronary Artery Disease (CAD) or Arteriovenous Malformation (AVM). Many human diseases are inherited or passed from parent to child in families. These diseases occur because of damage to a gene(s), the genetic material that is also called DNA. ...

Phase N/A

Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval Study

The AMPLATZER Muscular VSD Occluder was approved by the US Food and Drug Administration (FDA) in September, 2007. This study is designed to further evaluate the safety and effectiveness in subjects implanted with the AMPLATZER Muscular VSD Occluder.

Phase N/A

Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist

We planned an intra-individual study, where 20 adult patients with CHD (e.g. Fallot Tetralogy, s/p corrective surgery, single ventricle s/p Fontan operation, aortic and pulmonary artery stenosis) will undergo two examinations. Both scans are aimed to assess different diagnostic parameter like angiography, cardiac anatomy, ventricular volume and flow. The first ...

Phase

Reversibility by Sildenafil of Exercise-Induced Abnormal Right Ventricular Pressure Response in ASD and VSD-Operated Patients

13.3 Study design and protocol 13.3.1 Design: double-blind case-control cross-over study 13.3.2 Patients inclusion / exclusion criteria: The study consists of 12-16 patients from the main study (see main protocol) who are selected by following criteria - Abnormal right ventricular pressure response to exercise (cut-off 45 mmHg maximal RVSP during ...

Phase N/A

RAMYD Study - Evaluation of Arrhythmic Risk in Myotonic Dystrophy

Myotonic dystrophy type 1 (DM1, Steinert disease) is a multisystem disorder that affects, beside muscle, several other organs, including the heart. Cardiac involvement represents a major problem in the clinical management of patients, so that cardiac complications represent one of the primary causes of premature death in DM1. In particular ...

Phase

Genetics of Cardiovascular and Neuromuscular Disease

We are studying the genetics of human cardiovascular and neuromuscular disease. There are many different genetic regions that have been associated with the development of cardiomyopathy. An equal number of genetic regions have been associated with muscular dystrophy and there is overlap because some of the identical genes, when mutated, ...

Phase N/A

Evaluating the Infant Complex Congenital Heart Disease by Multidetector Computed Tomography

To test the ability of multi-detector spiral CT in evalting the infant complex congenital heart disease.

Phase N/A

Establish a CT Images Database of Patients With Congenital Heart Disease

Setup CT images database of congenital heart disease.

Phase N/A

Aortic Regurgitation After Surgical Repair of Outlet-Type Ventricular Septal Defect

Progression of aortic regurgitation (AR) in repaired outlet (juxta-arterial, muscular outlet and perimembranous outlet) ventricular septal defect (VSD) remains unclear. From 1987 to 2002, 411 patients with complete follow-up after repair of outlet VSD constituted the study population. Study end point was aortic valve replacement or mortality. Aortic valve replacement ...

Phase N/A