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Congenital Heart Disease Clinical Trials

A listing of Congenital Heart Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (161) clinical trials

Researchers at the University of Kentucky Gill Heart Institute are inviting you to learn more about a clinical study for blood pressure that is not adequately controlled with medications. Researchers are investigating a device to lower blood pressure that is beyond lifestyle and medication changes. This clinical study involves approximately ...

Phase N/A

Researchers at the University of Kentucky Gill Heart & Vascular Institute are inviting you to participate in a clinical research study evaluating an investigational implantable device designed to send electrical signals to balance the cardiovascular system. To learn more, visit:

Phase N/A

The purpose of the PSR platform is to provide continuing evaluation and periodic reporting ofsafety and effectiveness of market-released products for their intended use. PSR data will support post-market surveillance activities initiated by Medtronic and post-approval studies directed by a government and/or a regulatory authority. Conducting product surveillance in large ...

Phase N/A

A research study is evaluating the effects of an investigational dose of an FDA-approved medication for cardiovascular outcomes in adults who are overweight.

Phase N/A

The primary endpoint of this study is the time to first  occurrence of any component of the composite endpoint, as adjudicated by the Clinical  Endpoint Committee (CEC). Components of the primary endpoint are:               Cardiovascular (CV) death      Resuscitated cardiac arrest    Non-­fatal MI         Non-­fatal stroke 


Evaluation of the Microcirculation During the Corrective Surgery of Congenital Heart Defects in Children

Specific objectives: To test the usefulness of skin laser Doppler flowmetry monitoring (LDPM) in the non-invasive evaluation of endothelium-dependent microvascular reactivity during CPB in children. To investigate whether skin LDPM could be proposed as a clinical monitoring of tissue perfusion during CPB in pediatric cardiac surgery. To investigate the effects ...

Phase N/A

Improved Oral Health and Dental Care in Children With Congenital Heart Disease

Power analysis: Children with CHD are at high risk of developing caries (Stecksn-Blicks C et al 2004). In Swedish high-risk areas for developing caries, 12 % of three-year-old children had moderate and severe carious lesions (ICDAS II 3-6) and 11% initial carious lesions (ICDAS II 1-2) (Anderson et al 2016). ...

Phase N/A

Closure of Muscular Ventricular Septal Defects (VSDs) With the AMPLATZER Muscular VSD (MuVSD) Occluder - Post Approval Study

The AMPLATZER Muscular VSD Occluder was approved by the US Food and Drug Administration (FDA) in September, 2007. This study is designed to further evaluate the safety and effectiveness in subjects implanted with the AMPLATZER Muscular VSD Occluder.

Phase N/A

Ocular and Vision Problems in Patients After Fontan Operation

Numerous authors have described optic disc edema, globe flattening, choroidal folds which were thought to be part of the well-defined but still idiopathic syndrome of idiopathic intracranial hypertension. The pathogenesis of idiopathic intracranial hypertension is not well understood. Recent reports, however suggest that elevated cerebral venous pressure underlines the process. ...

Phase N/A

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

The purpose of this initiative is to improve care and outcomes for infants with HLHS by: 1) expanding the established NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, 2) improving implementation of consensus standards, tested ...

Phase N/A