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Liver Disorders Clinical Trials

A listing of Liver Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (163) clinical trials

Better Diagnostic Tools for Children and Adolescents With Acute Liver Failure and Chronic Liver Insufficiency

Research question: Liver disease in childhood and adolescence can present as chronic liver disease (CLD) or acute liver failure (ALF), with different interim stages, and with the possibility of a presentation with acute on chronic liver failure as well. At the department of Pediatrics at Rigshospitalet the investigators follow around ...

Phase N/A

Paracetamol Metabolism Research in Postoperative Hepatic Surgery

The main objective of this study was to evaluate the 5-day kinetics of plasma paracetamol levels in postoperative major hepatic surgery (resection greater than or equal to three hepatic segments) compared with less extensive liver resection and hepatic re-intervention. The clearance of indocyanine green is a marker of hepatic perfusion ...

Phase N/A

DILIN's Prospective Study

Liver injury due to prescription and non-prescription medication use is a medical, scientific and public health problem of increasing frequency and importance in the United States. Indeed, drug-induced liver injury (DILI) is the most important reason for non-approval, withdrawal, limitation in use and clinical monitoring by the Food and Drug ...

Phase N/A

Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation

The current standard for biopsy-based diagnoses of dysfunction of liver transplants is histology (the Banff system), an arbitrary international empirical consensus based on lesions and rules, similar in principle to the kidney, heart, and lung histology systems. Recent data-driven approaches using molecular and conventional technologies indicate that such systems frequently ...

Phase N/A

Lingual Muscle Training in Late-Onset Pompe Disease (LOPD)

This study is being done to test the effects of Lingual Muscle Therapy (LMT) in patients with Late-Onset Pompe Disease (LOPD) who have tongue weakness. The results of this study will help design future research studies about LMT in LOPD.

Phase N/A

ExAblate Transcranial MRgFUS for the Management of Treatment-Refractory Movement Disorders

The purpose of this study is to evaluate the safety and initial effectiveness of MRI-guided focused ultrasound thermal ablation of a designated area in the brain of patients suffering from movement disorder symptoms: FUS under MRI-guidance and MRI-based thermometry can be safely delivered to patients suffering from treatment-refractory movement disorders ...

Phase N/A

Liver Fibrosis in Sickle Cell Disease

Liver biopsy is the gold standard to examine the liver for iron deposits and histology. However, liver biopsy is invasive and involves a risk of bleeding and pain. Biopsy may also miss significant pathology if the small biopsy specimen is taken from an uninvolved part of the liver. Non-invasive techniques ...

Phase N/A

Hemodynamic Alterations in Liver Cirrhosis Validated by Non-invasive MR Compared to Invasive Assessment

Liver cirrhosis is a chronic disease characterized by a progressive accumulation of fibrosis, loss of liver function and portal hypertension leading to several hemodynamic changes.The exact pathophysiological mechanisms causing the hyperdynamic alterations in cirrhosis are not fully elucidated. Aim The aim of the study is to assess hemodynamic alterations in ...

Phase N/A

Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques

If you agree to take part in this study, you will have a CT scan that is done as part of your routine care. This CT scan will be done at the normal radiation dose. During this scan, you will also have a scan of the liver at a lower ...

Phase N/A

MRI to Assess the Effect of Non-selective Beta-blocker in Patients With Cirrhosis

Background Standardization and new therapeutic treatments of variceal bleeding has significantly reduced the mortality the last 25 years, but there is still a high 6-week mortality around 15-20% and 1-year mortality of about 40%. Cirrhotic patients without prophylactic treatment suffer a risk of 60% of re-bleeding within the first year ...

Phase N/A