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Ankylosing Spondylitis Clinical Trials

A listing of Ankylosing Spondylitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (25) clinical trials

24-Week trial comparing treatment with Study Medicine vs. placebo. Patient Inclusion Criteria: Age >/= 18 Diagnosis of definite AS Active AS Inadequate response to treatment. Patient Exclusion Criteria: Major Surgery within 8 weeks prior to screening Inflammatory Disease other than AS Treatment with Investigational Medication within 4 weeks Hepatitis B, ...

Phase

Do you have Ankylosing Spondylitis? You may qualify to participate in a clinical research study. IL-6Ra mAb is a randomized placebo controlled trial of an injectable IL-6Rmab for patient with active sacroileitis from anklyosing spondylitis with active joint disease who are not responding to NSAIDs and are biologic agent naive. ...

Phase

Ankylosing Spondylitis is painful and debilitating form of arthritis that affects the spine. The purpose of this study is to evaluate the effectiveness of the drug ixekizumab (LY2439821) compared to placebo over a 16 week period in patient's with radiographic axial spondyloarthritis (rad-axSpA). If you have been diagnosed with this ...

Phase

Local doctors are looking for people with Ankylosing Spondylitis (AS) for a clinical research study of an investigational drug. AS is a type of inflammatory arthritis that mostly affects the spine.

Phase

Local doctors are looking for people with Ankylosing Spondylitis (AS) for a clinical research study of an investigational drug. AS is a type of inflammatory arthritis that mostly affects the spine.

Phase

Etanercept Withdrawal And Retreament Study In Subjects With Nr-ax SpA

This multcenter, open-label, three period study will evaluate withdrawal and retreatment of etanercept in subjects with nr-ax SpA who achieved adequate response following 24 weeks of treatment.

Phase

Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases

Protocol: TRANSREG is a multicentric, uncontrolled, open-label study, comparing biological and clinical responses to the administration of low doses IL2 across 12 selected pathologies: rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, psoriasis, Behcet's disease, Wegener's granulomatosis, Takayasu's disease, Crohn's disease, ulcerative colitis, autoimmune hepatitis, sclerosing cholangitis and Gougerot-sjögren. Methods: Each ...

Phase

99mTc-rhAnnexin V-128 a Phase I/IIa Study in Patients With Rheumatoid Arthritis (RA) or Ankylosing Spondylitis (AS)

The objectives of the study are: Primary objective: - To determine the safety and tolerability of medical imaging with 99mTc-rhAnnexin V-128 Secondary objectives: - To determine the biodistribution, pharmacokinetics and radiation dosimetry of 99mTc-rhAnnexin V-128 - To demonstrate the time-dependant distribution and localization of 99mTc-rhAnnexin V-128 both in RA and ...

Phase

Adalimumab in Alleviating Inflammation in Patients With Axial Spondyloarthritis

Axial spondyloarthritis is an inflammatory rheumatic disease mainly affecting joints in the spine and the sacroiliac joints. Inflammatory pathways are likely the central link from axial spondyloarthritis to the known increased risk of atherosclerotic morbidity. Positron emission tomography (PET) is the most sensitive method to detect inflammatory foci in clinical ...

Phase

A Multicentre Study to Evaluate the Efficacy and Safety of ENIA11 in Patients With Ankylosing Spondylitis

This is a multi-center, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of ENIA11 in patients with ankylosing spondylitis. The study period for each patient will be 27 weeks, during which the patient will undergo screening for up to 21 days, and followed by treatment of 24 ...

Phase