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Ankylosing Spondylitis Clinical Trials

A listing of Ankylosing Spondylitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (28) clinical trials

24-Week trial comparing treatment with Study Medicine vs. placebo. Patient Inclusion Criteria: Age >/= 18 Diagnosis of definite AS Active AS Inadequate response to treatment. Patient Exclusion Criteria: Major Surgery within 8 weeks prior to screening Inflammatory Disease other than AS Treatment with Investigational Medication within 4 weeks Hepatitis B, ...

Phase

Do you have Ankylosing Spondylitis? You may qualify to participate in a clinical research study. IL-6Ra mAb is a randomized placebo controlled trial of an injectable IL-6Rmab for patient with active sacroileitis from anklyosing spondylitis with active joint disease who are not responding to NSAIDs and are biologic agent naive. ...

Phase

Ankylosing Spondylitis is painful and debilitating form of arthritis that affects the spine. The purpose of this study is to evaluate the effectiveness of the drug ixekizumab (LY2439821) compared to placebo over a 16 week period in patient's with radiographic axial spondyloarthritis (rad-axSpA). If you have been diagnosed with this ...

Phase

Local doctors are looking for people with Ankylosing Spondylitis (AS) for a clinical research study of an investigational drug. AS is a type of inflammatory arthritis that mostly affects the spine.

Phase

Local doctors are looking for people with Ankylosing Spondylitis (AS) for a clinical research study of an investigational drug. AS is a type of inflammatory arthritis that mostly affects the spine.

Phase

Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

The susceptibility to ankylosing spondylitis (AS) is largely genetically determined. Recent studies suggest that the severity of AS is also influenced by genetic factors. The goal of this study is to identify genes that influence the severity of AS. We hypothesize that genetic markers of susceptibility, including human leukocyte antigen ...

Phase N/A

An Observational Study to Evaluate Safety and Efficacy of Remsima in Patients With Ankylosing Spondylitis

The primary objective of this study is to assess the safety of Remsima™ in ankylosing spondylitis (AS) patients, in comparison with patients receiving other anti-TNF drugs, by evaluation of events of special interest (ESI) for up to 5 years from the first visit of each patient. In order to assess ...

Phase N/A

Progression of Spinal Fusion in Ankylosing Spondylitis

Spinal fusion is the clinical, radiological, and pathological hallmark of ankylosing spondylitis (AS). However, spinal fusion occurs slowly in AS. Serial radiographs rarely show changes over 2 years, and often 5 or more years are needed to demonstrate progression of spinal fusion. Methods that are more sensitive to changes in ...

Phase N/A

Assessment of SpondyloArthritis Society (ASAS) Classification and Diagnostic Criteria for Early Axial Spondyloarthritis (SpA)

Background: Existing criteria for AS/SpA such as mod. New York, ESSG, or Amor criteria for classification and/or diagnosis of spondyloarthritis have limitations when applied to early disease. Moreover, MRI is not part of any of the established criteria and the precise role of MRI in early axial disease has not ...

Phase N/A

Pilot Open Label Clinical Trial With Abatacept in Ankylosing Spondylitis

Clinical manifestations and prevalence of ankylosing spondylitisAnkylosing spondylitis (AS) is a chronic inflammatory disease which affects primarily the spine and the sacroiliac joints, but extraspinal structures such as peripheral joints, the enthesis (insertion of tendons/ligaments at bone), the eye (uveitis) and the aorta can also be involved. There is a ...

Phase