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Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (49) clinical trials

Dose-finding Pharmacokinetics Safety and Tolerability of Meropenem-Vaborbactam in Pediatric Subjects With Serious Bacterial Infections

In the current era of increased resistance to extended spectrum cephalosporins, carbapenem antimicrobial agents are frequently the antibiotics of "last defense" for the most resistant pathogens in serious infections, including those found in complicated Urinary Tract Infections (cUTI). The recent dissemination of serine carbapenemases (e.g. KPC) in Enterobacteriaceae in many ...

Phase

Study Evaluate the PK Profile of Dalbavancin in Hospitalized Infants and Neonates Patients With Known or Suspected Bacterial Infection

The purpose of this study is to evaluate the Pharmacokinetic (PK) profile of a single intravenous (IV) infusion dose of dalbavancin, and to evaluate the safety and tolerability of a single dalbavancin IV infusion.

Phase

Diagnostic Performance of a New Bio-marker During Bacterial Sepsis

Sepsis is a constant concern in ICU, frequent and severe, it requires early diagnosis and prompt implementation of the etiological treatment. The bacterial infections are the most common and are associated with high morbidity and mortality. Diagnosis is based on the detection of micro-organisms (bacteria) that can confirm the diagnosis ...

Phase N/A

A Study of Oral and Intravenous (IV) Tedizolid Phosphate in Hospitalized Participants Ages 2 to <12 Years With Confirmed or Suspected Bacterial Infection (MK-1986-013)

Part A (IV): - Group 1 (Cohort 1 and Cohort 2) (6 to <12 years) - Group 2 (Cohort 1 and Cohort 2) (2 to <6 years) Part B (Oral Suspension): - Group 3 (6 to <12 years) - Group 4 (2 to <6 years) In Cohort 1 of Group ...

Phase

Clinical and Immunological Efficiency of Bacterial Vaccines at Adult Patients With Bronchopulmonary Pathology

Methods: 1. IgG-antibodies against S.pneumoniae - solid-phase ELISA. 2. General levels of IgA, IgM, IgG, IgE in sera - radial immunodiffusion. 3. Phagocytic activity (granulocytes, monocytes), nitroblue tetrazolium test; activated T-lymphocytes (CD3+CD69+); activated B-lymphocytes (CD3-CD69+); absolute content of leukocytes; absolute and relative content of lymphocytes, granulocytes, monocytes, T-lymphocytes (CD3+, CD4+, ...

Phase

Evaluation of ATx201 as a Topical Antibiotic Agent

Treatment of skin infections, including infected atopic dermatitis, is plagued by inactivity of or resistance towards the main topical antibiotics. Accordingly, the infections are either not effectively treated or harsher systemic antibiotics with side effects are needed. Infections in atopic dermatitis are predominantly caused by Staphylococcus aureus and various species ...

Phase

Evaluating a Host-response Based Diagnostic for Distinguishing Between Bacterial and Viral Etiology in Patients With Lower Respiratory Tract Infection (LRTI)

The purpose of this study is to validate the diagnostic accuracy of a novel host-response based diagnostic tool for differentiating between bacterial and viral etiologies in adult patients aged 18 years and older with clinical suspicion of lower respiratory tract infections (LRTI)

Phase N/A

Host-based Immunoassay for Differentiating Bacterial From Viral Infections (Post-marketing Study of ImmunoXpert )

This is a retrospective external field study of a novel in vitro diagnostic (IVD) assay (ImmunoXpert™). The study will involve reviewing the medical charts of 4500 pediatric patients that were tested using ImmunoXpert™ as part of the routine workup for acute febrile illness. ImmunoXpert™ uses a computer algorithm to combine ...

Phase N/A

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

The purpose of this study is to characterize the PK ( Pharmacokinetics) of understudied drugs administered to children per standard of care as prescribed by their treating caregiver. This will be accomplished by the collection of biological samples during the time of drug administration per standard of care as prescribed ...

Phase N/A