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Aneurysm Clinical Trials

A listing of Aneurysm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (10) clinical trials

Estrogen Therapy as Prevention in the Progression of Aneurysm (EPPA) Trial

This is a prospective, randomized, placebo-control trial to test the effect of estradiol in the prevention of progression of cerebral aneurysms. To evaluate the effect, each subject will be treated with either oral estradiol or placebo for 6 months. Subjects will be randomly assigned to 1 of 2 groups as ...

Phase

Cyclosporine A in Patients With Small Diameter Abdominal Aortic Aneurysms

Abdominal aortic aneurysms (AAAs) expose patients to death caused by aortic rupture. Although screening of AAAs has been shown to decrease AAA-related mortality, translation into medical practice of screening is limited because there is no specific treatment to limit growth of AAAs below diameter thresholds for open surgery or stent ...

Phase

Vascular Protective Effect of Rosuvastatin in Arteriovenous Fistula

Background In Taiwan, diabetic nephropathy is the second most common cause of end-stage renal disease (ESRD), but diabetic patients engender 12% more expense for care of dialysis than non-diabetic patients. ESRD patients with diabetes are also more frequently hospitalized due to problems such as failure of vascular access. Hemodialysis necessitates ...

Phase

Use of Fish Oil to Reduce Inflammation During Endovascular Abdominal Aortic Repair

In this 2:1 double-blind, randomized, placebo controlled trial, subjects will be given an active drug of n-3 polyunsaturated fatty acids (PUFAs) or a placebo soybean oil for about two weeks prior to an endovascular abdominal aortic repair (EVAR) and subsequently six months after the procedure. An EVAR is known to ...

Phase

Evaluation of Predictors of Aortic Aneurysm Growth and Rupture

Aim#1: Prospective Contrast Ultrasound (CUS) imaging of patients with AAA to predict AAA growth and test gender differences in rate of growth and rupture. Aim#2: Serum biomarker testing of patient with AAA. CUS findings will be correlated with serum biomarkers and AAA wall histology. Prospective Contrast Ultrasound imaging of patients ...

Phase

Aneurysmal Subarachnoid Hemorrhage Trial RandOmizing Heparin

The primary objective of this study is to investigate the safety and clinical effect of a continuous low-dose intravenous unfractionated heparin (LDIVH) infusion for the prevention of aneurysmal subarachnoid hemorrhage (aSAH) induced neurocognitive dysfunction and other delayed neurological deficits. Additionally, increased blood and CSF levels of certain inflammatory biomarkers (IL-6, ...

Phase

Evaluation of Branch Endografts in the Treatment of Aortic Aneurysms

Study Update as of 10/31/2017;84 subjects successfully have been implanted with the Zenith t-Branch Device to date and recruitment is ongoing.

Phase

Doxycycline Treatment to Prevent Progressive Coronary Artery Dilation in Children With Kawasaki Disease

This research study attempts to reveal whether coronary artery dilation in patients with Kawasaki disease refractory to standard therapy could be prevented using a matrix metalloproteinase inhibitor: doxycycline. Hypothesis The investigators hypothesize that oral administration of doxycycline for two weeks during the acute phase of Kawasaki disease (KD) effectively blocks ...

Phase

Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex Abdominal Aortic Aneurysms Using CMDs

This is an investigator sponsored Investigational Device Exemption (IDE) aimed to assess the use of the Custom Made Device (CMD) to repair juxtarenal aneurysms, suprarenal and type IV thoracoabdominal aneurysms in standard risk patients having appropriate anatomy. This study is a prospective, single-center, non-randomized, single-arm study.

Phase

A Clinical Study of the Safety and Efficacy of the Relay Thoracic Stent-Graft in Patients With Thoracic Aortic Pathologies

The purpose of this clinical trial is to assess and evaluate the safety and efficacy of the Relay Thoracic Stent-Graft in subjects with TAA compared to surgical repair subjects. This is a phase II multi-center, non-blinded, non-randomized study of treatment of the Relay Thoracic Stent-Graft in subjects with thoracic aortic ...

Phase