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Kidney Failure Clinical Trials

A listing of Kidney Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (188) clinical trials

Safety and Efficacy Study of BCD-066 Compared to Aranesp for Anemia Treatment in Chronic Kidney Disease Patients

In this study CKD patients on dialysis previously treated by short-acting epoetins will switch to one of darbepoetin alfa products - BCD-066 (experimental arm) or Aranesp (active comparator) to maintain previously achieved target level of hemoglobin (100-120 g/l). Patients will be treated for 52 weeks. IV iron supplementation will be ...

Phase

Prevalence of Chronic Kidney Disease and Its Association With Clinical Outcome in Patients With Coronary Heart Disease

The primary aim of the study is to evaluate the prevalence of chronic kidney disease(CKD) in patients with stable coronary heart disease. The secondary aims include: 1. To evaluate the awareness of CKD in patients with stable coronary heart disease. 2. To find out risk factors that is associated with ...

Phase N/A

Safety and Efficacy of the Sirolimus-Eluting Collagen Implant to Assess AV Fistula Outcomes in Patients on Hemodialysis

The purpose of this study is to determine whether the use of the Sirolimus-eluting Collagen Implant will improve AV Fistula outcomes, including time to first dialysis and suitability for dialysis at 6 months, in subjects undergoing surgical creation of an AV fistula for providing vascular access for hemodialysis.

Phase

Contribution of Renal Function to Endothelial Dysfunction in Living Kidney Donors and Transplant Recipients

HYPOTHESIS BACKGROUND: Chronic kidney disease (CKD) is associated with endothelial dysfunction, but the link between cardiovascular risk and CKD is difficult to establish because other conditions such as diabetes, hypertension and transplant-related factors are present in these patients. Living donors are healthy individuals that represent a near-ideal experimental model of ...

Phase N/A

Increased Adsorption Membranes During Cardiopulmonary Bypass

After informed consent, on those patients randomized to CPB-OXIRIS®, PrismafleX eXeed™ II (Baxter Gambro) with OXIRIS® set will be irrigated with saline during preparation and irrigation of CPB circuit. PrismafleX eXeed™ II (Baxter Gambro) with OXIRIS® set will then be connected to CPB circuit. Blood flow between 200-250 ml/min will ...

Phase N/A

Clinical Evaluation of a Vascular Anastomotic Connector System

This is a pivotal multicenter, prospective, non-randomized adaptive design study. The planned study enrollment is a minimum of 104 evaluable subjects who require AV graft placement for hemodialysis and who meet the entry criteria. However, the study will allow for a maximum enrollment of 252 subjects, including up to 185 ...

Phase N/A

Standard vs. Accelerated Initiation of RRT in Acute Kidney Injury (STARRT-AKI: Principal Trial)

Acute kidney injury (AKI) is a common and devastating complication of critical illness. Once AKI is established, treatment is largely supportive and no intervention has been found to restore kidney function or improve overall survival. Renal replacement therapy (RRT), usually in the form of hemodialysis, is frequently needed to manage ...

Phase

Medico-economic Evaluation of a Telemedicine System for the Management of Chronic Renal Failure

Three populations are recruited with the following inclusion criteria: - age ≥ 18 years; - ability to use a tablet device (alone or with assistance); - population 1: stabilised stage 3B or stage 4 CKD with nephrology management of less than 3 years; - population 2: stage 5D CKD treated ...

Phase N/A

Belatacept in Kidney Transplantation of Moderately Sensitized Patients

This exploratory single-center, open-label safety and efficacy study will enroll 20 adult kidney transplants candidates, moderately sensitized against their deceased donor and at-risk for delayed graft function (DGF), to receive Belatacept (days 0,5, weeks 2,4,8 and 12 (10 mg/kg), and every 4 weeks thereafter (5 mg/kg)), plasma exchange (once before ...

Phase

Clinical Trial in Patients With Hypertension and Left Ventricular Dysfunction

The scope of this entire study is to examine the patients as follows:: Complete Echocardiographic Study including the index of left ventricular mass and relative wall thickness (RWT), measurement acquired from left parasternal longitudinal axis. Further assessment will be diastolic function and filling pressures of the left ventricle using all ...

Phase N/A