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Kidney Failure Clinical Trials

A listing of Kidney Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (546) clinical trials

Evaluate the potential effect of hepatic or renal impairment on the pharmacokinetics, safety and tolerability of BAY 1841788 (ODM-201).


RESTARRT is a clinical research study that is testing whether a combination of several medications can reset the immune system and help it accept a new kidney without the need for life-long immunosuppression. The medications used in RESTARRT are anti-thymocyte globulin (ATG), rituximab, mycophenolate mofetil (MMF), tacrolimus and sirolimus. Participants ...

Phase N/A

Meridien Research needs volunteers for a new clinical trial of a triglyceride-lowering medication. Call Meridien Research today at 813-877-8839 to see if you qualify!

Phase N/A

Safety Tolerability and Activity of TNT009 in Healthy Volunteers and Patients With Complement Mediated Disorders

Study TNT009-01 is a First in Human (FIH) study that uses an Integrated Protocol Design. This Phase 1 study protocol will comprise three sub-parts: a Single Ascending Dose (SAD) and Multiple Ascending Dose (MAD) study in normal male and female human volunteers (NHVs), and a Multiple Dose (MD) study in ...


Safety and Efficacy Study of BCD-066 Compared to Aranesp for Anemia Treatment in Chronic Kidney Disease Patients

In this study CKD patients on dialysis previously treated by short-acting epoetins will switch to one of darbepoetin alfa products - BCD-066 (experimental arm) or Aranesp (active comparator) to maintain previously achieved target level of hemoglobin (100-120 g/l). Patients will be treated for 52 weeks. IV iron supplementation will be ...


Prevalence of Chronic Kidney Disease and Its Association With Clinical Outcome in Patients With Coronary Heart Disease

The primary aim of the study is to evaluate the prevalence of chronic kidney disease(CKD) in patients with stable coronary heart disease. The secondary aims include: 1. To evaluate the awareness of CKD in patients with stable coronary heart disease. 2. To find out risk factors that is associated with ...

Phase N/A

Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes

The purpose of this study is to determine whether the use of the Sirolimus-eluting Collagen Implant will improve AV fistula outcomes, including suitability for dialysis, and the proportion of subjects who maintain primary patency six months following the index procedure in subjects undergoing surgical creation of an AV fistula for ...


Contribution of Renal Function to Endothelial Dysfunction in Living Kidney Donors and Transplant Recipients

HYPOTHESIS BACKGROUND: Chronic kidney disease (CKD) is associated with endothelial dysfunction, but the link between cardiovascular risk and CKD is difficult to establish because other conditions such as diabetes, hypertension and transplant-related factors are present in these patients. Living donors are healthy individuals that represent a near-ideal experimental model of ...

Phase N/A

Increased Adsorption Membranes During Cardiopulmonary Bypass

After informed consent, on those patients randomized to CPB-OXIRIS, PrismafleX eXeed II (Baxter Gambro) with OXIRIS set will be irrigated with saline during preparation and irrigation of CPB circuit. PrismafleX eXeed II (Baxter Gambro) with OXIRIS set will then be connected to CPB circuit. Blood flow between 200-250 ml/min will ...

Phase N/A

Clinical Evaluation of a Vascular Anastomotic Connector System

This is a pivotal multicenter, prospective, non-randomized adaptive design study. The planned study enrollment is a minimum of 104 evaluable subjects who require AV graft placement for hemodialysis and who meet the entry criteria. However, the study will allow for a maximum enrollment of 252 subjects, including up to 185 ...

Phase N/A