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Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (54) clinical trials

Copper 64Cu-DOTA-Daratumumab Positron Emission Tomography in Diagnosing Patients With Relapsed Multiple Myeloma

PRIMARY OBJECTIVES: I. To assess safety and tolerability of unlabeled daratumumab followed by 64Cu-DOTA-daratumumab positron emission tomography, at each dose level, by evaluation of toxicities including: type, frequency, severity, attribution, time course and duration. SECONDARY OBJECTIVES: I. Generate initial estimates of the biodistribution of the 64Cu-DOTA-daratumumab and the preferred dose ...


Study of Daratumumab Ixazomib and Dexamethasone in Previously Treated Amyloid Light Chain (AL) Amyloidosis

Study Drug Administration: If participant is found to be eligible to take part in this study, participant will receive daratumumab, ixazomib, and dexamethasone. All participants will receive the study drugs at the same doses. Dexamethasone will be given at a lower dose during Cycle 1 and then a higher dose ...


Registry for Adults With Plasma Cell Disorders (PCD's)

OBJECTIVES Primary To create a Registry (to be called the PCD Registry) of PCD patients To have participating patients complete an assessment at enrollment and to repeat the assessment longitudinally over time. Secondary To gather information, including patterns of patient care, that would lend support for future research in the ...

Phase N/A

Mitochondrial Function in Transthyretin Amyloidosis

Systemic amyloidosis are a family of diseases induced by misfolded and/or misassembled proteins. Extracellular deposits of these proteins disrupt vital organ function. Two types of amyloid commonly infiltrate the heart: immunoglobulin light-chain amyloid and transthyretin (TTR) amyloid. Among the TTR variants that predominantly target the heart, the valine to isoleucine ...

Phase N/A