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Chronic Pain Clinical Trials

A listing of Chronic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (377) clinical trials

Open-Label Single-Arm Single-Center Study of Basivertebral Nerve Ablation Treatment of Chronic Low Back Pain

This is a prospective, open-label, single-arm, single-center study. There is no randomization or blinding. Subjects will receive the Intracept System procedure to treat one or two motion segments at L3/L4, L4/L5, or L5/S1 as identified by Modic Type 1 or 2 changes.

Phase N/A

Prospective Randomized Multi-center Study Intraosseous Basivertebral Nerve Ablation for Treatment of CLBP

Subjects in the RF Ablation arm will be followed for 24 months following treatment. Control arm subjects will be offered optional crossover treatment after 12 month follow-up visit and will be followed for an additional 6 months following crossover.

Phase N/A

Oxygenation of Paravertebral Muscles During Exercise in Chronic Low Back Pain Patients

The study evaluate paraspinal aerobic metabolism of chronic low back pain patients and healthy people during an original and standardized isokinetic protocol. The aim of this study is to determine a potential alteration of muscular aerobic metabolism in low back pain patients, in order to establish the underlying cause of ...

Phase N/A

Chronic Lumbosacral Radiculopathy: Impact of an Analgesic Dietary Intervention on Pain & Function

Lumbar radiculopathy is a fairly common pain syndrome which may result in chronic, severe disability. There are few successful treatment options for patients with persistent lumbosacral radicular pain (LRP) that does not respond to conventional approaches. A fundamental biologic mechanism of chronic LRP, as well as other chronic pain syndromes, ...

Phase N/A

Preoperative Gabapentin for Chronic Pain After Thoracotomy (GABATHOMIE).

Randomized, double blind study enrolling 200 adults undergoing thoracotomy. Patients receive either 75 mg hydroxyzine before surgery and placebo 3 times daily for 10 days or 1200 mg gabapentin before surgery continued for 10 days. All patients receive also a thoracic epidural analgesia. Assessment of chronic pain at 3 month ...

Phase

Autologous Tolerogenic Dendritic Cells for Treatment of Patients With Rheumatoid Arthritis

A phase I dose-escalating clinical trial will be conducted to determine the safety and tolerability of a single intra-articular injection (into the knee joint) of autologous tolerogenic dendritic cells, and to enable selection of a suitable dose regimen for phase II trial. The primary objective of the phase I study ...

Phase

Clinical Electrophysiology Assessment for Low Back Pain

Participants: One hundred adults with non specific chronic low back pain (LBP) will be recruited. Methodology: A prospective correlation study between clinical examination and electrophysiology assessment. This project will perform carefully with a definitive chronic low back pain (LBP). Firstly, we will compare the surface EMG features from patients with ...

Phase N/A

Clinical Outcomes of the Freedom Spinal Cord Stimulation (SCS) System for the Management of Chronic Back and Leg Pain

This study evaluates the Freedom SCS (spinal cord stimulation) System for the treatment of chronic back and leg pain. Patients who have been diagnosed with failed back surgery syndrome (FBSS) will receive a stimulator device for treatment of their pain.

Phase N/A

Lidocaine Infusions for Chronic Pain in Children

Reports have shown that intravenous lidocaine infusions have been effective in relieving chronic pain that has been resistant to other therapies, with minimal side effects. We would like to determine whether severity of pain and degree of chronic-pain related disability could be reduced with lidocaine infusion in children and to ...

Phase

A Single Ascending Dose Study of Safety and Tolerability of STA363 Compared to Placebo in 15 Patients With Chronic Discogenic Low Back Pain

A phase I, randomized, double-blinded, placebo-controlled, single ascending dose study to investigate the safety, local tolerability and transformation of nucleus pulposus following intradiscal injection of STA363 or placebo in patients with discogenic low back pain. 15 patients will participate in either of 3 dose groups, each comprising 5 patients: Group ...

Phase