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Chronic Pain Clinical Trials

A listing of Chronic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (360) clinical trials

Internet-based Pain Self-management for Persons With Acute Recurrent and Chronic Pancreatitis Pain

Acute recurrent pancreatitis (ARP) and chronic pancreatitis (CP) are associated with high disease burden across the lifespan. Recurring abdominal pain is the most prevalent and distressing symptom. Pain severity reduces health-related quality of life for individuals with CP and is associated with increased fatigue, anxiety and depressive symptoms, lower general ...

Phase N/A

Genetic Determinants of Amitriptyline Efficiency for Pain Treatment

Background Pain is defined as an ongoing unpleasant sensory experience, which can be classified according to three major, although overlapping, etiologies: nociceptive, inflammatory and neuropathic pain. Antidepressants are widely used as co-analgesics in the management of chronic pain. An overview of different substances and their relation to their mechanism of ...

Phase

Open-Label Single-Arm Single-Center Study of Basivertebral Nerve Ablation Treatment of Chronic Low Back Pain

This is a prospective, open-label, single-arm, single-center study. There is no randomization or blinding. Subjects will receive the Intracept System procedure to treat one or two motion segments at L3/L4, L4/L5, or L5/S1 as identified by Modic Type 1 or 2 changes.

Phase N/A

Patient Controlled Intrathecal Analgesia With Bupivacaine for Chronic Low Back Pain

Methodology /Technical Approach: Seventeen patients who are already using SynchroMed II pump containing an admixture of bupivacaine and an opioid and using PTM doses will receive Solution A during the first week of the study and will be crossed over to Solution B during the second week of the study. ...

Phase

Prospective Randomized Multi-center Study Intraosseous Basivertebral Nerve Ablation for Treatment of CLBP

Subjects in the RF Ablation arm will be followed for 24 months following treatment. Control arm subjects will be offered optional crossover treatment after 12 month follow-up visit and will be followed for an additional 6 months following crossover.

Phase N/A

A Mobile Intervention to Reduce Pain and Improve Health (MORPH)

Chronic pain has emerged as an urgent age-related health issue that significantly effects physical functioning and quality of life, with the unfavorable effects worsened by both obesity and sedentary behavior. The annual cost of pain in the United States is nearly 30% higher than the combined costs of cancer and ...

Phase N/A

Botulinum Toxin for Pelvic Pain in Women With Endometriosis

Chronic pelvic pain associated with endometriosis is poorly understood. Some women with chronic pelvic pain have muscle spasm of their pelvic muscles. Muscle spasm may be a significant part of pain in women with endometriosis and other types of chronic pelvic pain. Botulinum toxin injection is widely used to treat ...

Phase

A Study of MEDI7352 in Painful Osteoarthritis of the Knee

An interleaved SAD/MAD Study to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of MEDI7352 in subjects with painful osteoarthritis of the knee.

Phase

A Pilot Trial of Combined Exercise and Education in Rural Community-Dwelling Individuals With Chronic Low Back Pain

This study will determine whether a supervised graded exercise training emphasizing motor control exercise (MCE) combined with patient education (PE) consistent with the current guidelines will be more effective in improving pain, functional disability, and back beliefs in rural community-dwelling individuals with CNLBP following 6-weeks of therapeutic session. Participants will ...

Phase N/A

Precision Pain Management for Major Abdominal Surgery in Colorectal Surgery

The primary objectives of this study are to evaluate the potential for preoperative pharmacogenomics (PGx) testing to positively influence postoperative opioid use through visual analog scale (VAS) guided administration of narcotic equivalent and lower pain scores as measured by OBAS in patients undergoing major abdominal surgery.

Phase N/A