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Knee Surgery Clinical Trials

A listing of Knee Surgery medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (53) clinical trials

A Study to Evaluate the Safety and Efficacy of Intravenous JNJ-64179375 Versus Oral Apixaban in Participants Undergoing Elective Total Knee Replacement Surgery

This study has 2 parts, dose escalation and dose-response evaluation, and will be conducted in participants undergoing primary unilateral elective Total Knee Replacement (TKR) surgery. Participants will participate in either Part 1 or Part 2 of study only. The study will be conducted in 3 phases: an up to 30-day ...


Hypnosis for Symptom Management in Elective Orthopedic Surgery

Patients will be recruited by through orthopedic surgery clinics or contacted by after pre-screening via chart review and given an information brochure. If they are interested in the trial will be emailed or given a paper copy of the consent form and scheduled for a single additional visit in the ...

Phase N/A

Blood Flow Restriction Training in Patients With Weight Bearing Restrictions After Knee Surgery

After a cartilage or meniscus repair in the knee joint, the patients experience a pronounced and persistent decrease of knee-extension strength in the operated leg, which negatively affect patients' functional performance and quality of life. A possible novel exercise modality to increase muscle strength early is a moderate blood flow ...

Phase N/A

iCORE: Collaborative Orthopedics Outcomes Registry

The goal of this registry is to review the data collected and research ways to improve patient safety, quality of care, and medical decision-making, reduce medical spending, and help advance orthopedic science and bioengineering.

Phase N/A

Comparison Between Kinesiotaping and Cold Therapy After Total Knee Arthroplasty

Total knee arthroplasty (TKA) has been established as a valuable procedure patients with end-stage osteoarthritis and the rates of elective TKA are increasing steadily each year. Ninety percent of patients reported reduced pain, improved functional ability, and greater health related quality of life after TKA. Kinesiotaping (KT), a type of ...

Phase N/A

Impact of Different Educational Approaches on Post-operative Opiate Utilization After Elective Lower Extremity Surgery

Hypothesis: The primary hypothesis is that the educational intervention provided prior to the surgery and prior to the prescription, will result in a greater understanding and awareness of the deleterious effects of long-term use of opioid based medications, and in turn reduce utilization post-operatively in the long-term (6 months). Specific ...

Phase N/A

Analgesic Efficacy of Saphenous Nerve Blockade for Outpatient Knee Anterior Cruciate Ligament Surgery

The purpose of this study is to determine whether blockade of the saphenous nerve can provide the same degree of analgesia postoperatively for ACLS as a femoral nerve block without resulting motor blockade enhancing shortening of hospital stay en functional outcome.

Phase N/A

Impact of a Technique of Massage During the First Week of Hospitalization on the Recycling of the Mobility of the Knee Further to the Installation of Knee Replacement

During fthe first postoperative days, physiotherapists supported patients with knee replacement in orthopaedics of Saint-Junien's and Limoges' hospitals. This support includes movements of the leg in active and non active motions, without any help and with an arthromotor, and involves walking rehabilitation. The investigators would like to complete the physiotherapist's ...

Phase N/A

fMRI and Central Sensitization in Chronic Knee Osteoarthritis. A Pre and Post TKR Study

Painful osteoarthritis (OA) is the 4th largest cause of disability in the UK. Preoperative temporal summation, a measure of central pain facilitation, has been shown to predict postoperative pain after total knee replacement surgery (TKR). The assessment of the brain's response to noxious stimuli using non-invasive functional MRI (fMRI) may ...

Phase N/A

Dose Dependent Effects of tDCS on Post-Operative Pain

The proposed study employs a randomized, double-blind, sham-controlled design to evaluate the effects of tDCS on pain among Veterans receiving unilateral total knee arthroplasty (TKA) and unilateral total hip arthroplasty (THA). Further, this study will examine dose-dependency of the tDCS analgesic effects. 120 patients undergoing TKA will be randomly assigned ...